Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet CCL20.
Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER
Sammanfattning : This thesis is focused on the analysis of Hodgkin lymphoma (HL), in particular the complex interaction between the malignant cells and the abnormally behaving bystander cells, and this complexity of the inflammatory infiltrate in HL constantly challenge scientists. The common thread in this thesis is the usage of gene expression profiling of whole tumour tissues, laser-captured Hodgkin Reed Sternberg (H-RS) cells and of cell-lines. LÄS MER
Sammanfattning : Preeclampsia is a major challenge to obstetricians, due to its impact on maternal and fetal morbidity and mortality and the lack of preventive and treatment strategies. The overall aim of this thesis is to increase the knowledge of the pathogenesis of preeclampsia including the role of inflammation, angiogenesis and coagulation, both locally at the fetomaternal interface and in the maternal circulation. LÄS MER
Sammanfattning : Psoriasis is a common immune-mediated disease, where an increased prevalence of extra cutaneous diseases and mortality is observed. Common inflammatory mechanisms are implicated. LÄS MER
Sammanfattning : Paper I. Effects of low molecular weight heparin on the polarization and cytokine profile of macrophages and T helper cells in vitro. Sci Rep 2018. LÄS MER