Sökning: "CCL20"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet CCL20.

  1. 1. Vibrio cholerae modulates the immune defense of human gut mucosa

    Författare :Aziz Bitar; Marie-Louise Hammarström; Sun Nynt Wai; Mikael Rehn; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; intestinal epithelial cell; duodenum biopsy; acute cholera; immunomodulation; microRNA; OMV; cytokine; T84 monolayer; miR-146; miR-155; VCC; PrtV; hemolysis; IL-8; TNF-a; IL-1b; IL-18; CCL20; IRAK2; inflammation; mikrobiologi; Microbiology; immunologi; Immunology;

    Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER

  2. 2. Transcriptome based analysis of Hodgkin lymphoma : Insights into the microenvironment

    Författare :Anna Birgersdotter; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Hodgkin lymphoma; Epstein-Barr virus; gene expression; tissue culture; cell-line models;

    Sammanfattning : This thesis is focused on the analysis of Hodgkin lymphoma (HL), in particular the complex interaction between the malignant cells and the abnormally behaving bystander cells, and this complexity of the inflammatory infiltrate in HL constantly challenge scientists. The common thread in this thesis is the usage of gene expression profiling of whole tumour tissues, laser-captured Hodgkin Reed Sternberg (H-RS) cells and of cell-lines. LÄS MER

  3. 3. Aspects of inflammation, angiogenesis and coagulation in preeclampsia

    Författare :Roland Boij; Leif Matthiesen; Jan Ernerudh; Maria Jenmalm; Göran Berg; Henrik Hagberg; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Preeclampsia is a major challenge to obstetricians, due to its impact on maternal and fetal morbidity and mortality and the lack of preventive and treatment strategies. The overall aim of this thesis is to increase the knowledge of the pathogenesis of preeclampsia including the role of inflammation, angiogenesis and coagulation, both locally at the fetomaternal interface and in the maternal circulation. LÄS MER

  4. 4. Studies of the Systemic Inflammation in Psoriasis

    Författare :Gunnthorunn Sigurdardottir; Charlotta Enerbäck; Cecilia Bivik; Ingrid Synnerstad; Maria Bradley; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Psoriasis is a common immune-mediated disease, where an increased prevalence of extra cutaneous diseases and mortality is observed. Common inflammatory mechanisms are implicated. LÄS MER

  5. 5. Clinical and immunological aspects on recurrent pregnancy loss

    Författare :Valentina Bruno; Jan Ernerudh; Maria Jenmalm; Emilio Piccione; Adalgisa Pietropolli; Carlo Ticconi; Udo R. Markert; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Paper I. Effects of low molecular weight heparin on the polarization and cytokine profile of macrophages and T helper cells in vitro. Sci Rep 2018. LÄS MER