Sökning: "Molekylär neurogenetik"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Molekylär neurogenetik.

  1. 1. The Epigenetic Impact of Transposable Elements in Human Brain Development

    Författare :Per Ludvik Brattås; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transposable elements; epigenetics; neural stem cells; human brain development; gene regulation; human brain evolution;

    Sammanfattning : .... LÄS MER

  3. 2. Transposable Elements in Neural Progenitor Cells

    Författare :Liana Fasching; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable Elements; TRIM28; Epigenetic Regulation; Gene Expression; Neural Progenitor Cells;

    Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER

  4. 3. Transposable Elements in the Healthy and Diseased Human Brain

    Författare :Raquel Garza; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transposable elements; Neuroscience; Neuroinflammation; Evolution; Epigenetic regulation; Bioinformatics;

    Sammanfattning : .... LÄS MER

  5. 4. Development and Applications of in vitro Models to Study Human Brain Evolution and Disease

    Författare :Daniela Grassi; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural reprogramming; Neural differentiation; Brain development; Huntington s disease; Induced Neuron; Neural Progenitor Cell; Brain evolution;

    Sammanfattning : Neuroscience focusing on human development and disease has long been hampered due to ethical reasons, low tissue availability, and low translatability from animal models. To circumvent these obstacles, we have developed two methods for the investigation of human neural cells in culture. LÄS MER

  7. 5. The Regulatory Role of microRNAs in the Mouse and Human Brain

    Författare :Rebecca Petri; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; Argonaute; AGO-RIP; let-7; miR-125; adult neurogenesis; olfactory bulb; autophagy; transposable elements; LINE-2; Huntington’s disease;

    Sammanfattning : microRNAs (miRNAs) are 20-24 nucleotides small, single-stranded, non-coding RNAs. They associate with Argonaute (AGO) proteins and exert their function by inhibition or degradation of messenger RNAs. LÄS MER