Sökning: "blood separation"

Visar resultat 1 - 5 av 114 avhandlingar innehållade orden blood separation.

  1. 1. Clinical applications of acoustophoresis in blood based diagnostics

    Författare :Klara Petersson; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Acoustofluidics; Ultrasound; Microfluidics; Blood; Blood Separation; Blood plasma; Lab-on-a-chip; Point-of-care; Blood diagnostics;

    Sammanfattning : In this thesis, acoustofluidics has been used to process blood samples as a sample preparation step prior to biomarker detection. This is often required as the large amount of blood cells otherwise can interfere with the detection method. Acoustofluidics means moving particles or cells with acoustic forces within microfluidic channels. LÄS MER

  2. 2. Acoustofluidic preparation of whole blood components

    Författare :Anke Urbansky; NanoLund: Centre for Nanoscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; acoustophoresis; ultrasound; microfluidics; cell separation; blood; blood fractionation;

    Sammanfattning : Whole blood is rich in information about the physical state of an individual and is routinely used in a variety of clinical and research applications. In this thesis, the use of a microfluidic technique called acoustophoresis for separation of different blood components is explored. LÄS MER

  3. 3. Fat contamination of pericardial suction blood in cardiac surgery : clinical and experimental studies in perspectives of transfusion logistics

    Författare :Micael Appelblad; Gunnar Engström; Krister Lindmark; Anders Jeppsson; Umeå universitet; []
    Nyckelord :Surgery; blood transfusion; cardiopulmonary bypass; pericardial suction blood; fat contamination; lipid microemboli; density separation; surface adsorption; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Introduction: During cardiac surgery aided by cardiopulmonary bypass (CPB) the autotransfusion of pericardial suction blood (PSB) is regarded mandatory to limit allogeneic blood exposure. PSB is however proposed as a source of lipid microemboli and to contribute to brain damage. LÄS MER

  4. 4. Acoustic Forces in Cytometry and Biomedical Applications: Multidimensional Acoustophoresis

    Författare :Carl Grenvall; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Acoustophoresis; Microfluidics; Ultrasound; Multinode; Cell Sorting; Particle Positioning; Cytometry; Lab-on-a-Chip; µTAS; Binary Separation; Acoustic Barriers; Acoustic Particle Manipulation; Acoustic Standing Waves; Blood Separation; Milk Analysis;

    Sammanfattning : Over the last decades the ongoing work in the fields of Lab-on-a-Chip and Micro-Total-Analysis-Systems has led to the discovery of new or improved ways to handle and analyse small volumes of biofluids and complex biosuspensions. The benefits of working on the microscale include: miniaturization of the analysis systems with less need for large sample volumes; temporal and spatial control of suspended particle/cell positions; low volume sheath flow lamination or mixing; novel separation techniques by using forces inherent to the microscale domain; precise regulation of sample temperatures and rapid analysis with less volumes needed to be processed. LÄS MER

  5. 5. Assessment of eosinophil degranulation in allergic diseases and experimental models

    Författare :Monika Malm-Erjefält; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood; histochemistry; cytochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; animal morphology; Animal anatomy; Djurs anatomi och morfologi; Haematology; cytoplasmic granules ; Hematologi; Respiratory system; extracellulära vätskor; Andningsorganen; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Klinisk biologi; Pharmacological sciences; Histology; cell separation ; mice; animal models ; biological marker ; transmission electron microscopy allergy; cell degranulation ; Clinical biology; extracellular fluids; eosinophils;

    Sammanfattning : In allergic disorders, the eosinophilic granulocytes migrate to affected tissues and release granule proteins with cytotoxic, immunoregulatory, and remodeling-promoting properties. Given that degranulation is reflected by a loss in eosinophil granule density of living cells, or by cell membrane rupture and release of intact granules, these morphological changes may represent a biomarker of the allergic disease. LÄS MER