Sökning: "Smooth muscle"

Visar resultat 26 - 30 av 352 avhandlingar innehållade orden Smooth muscle.

  1. 26. Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

    Författare :Lisa Berglund; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular smooth muscle; proliferation; A-285222; osteopontin; AIF-1; diabetes; vascular disease; calcium; glucose; NFAT;

    Sammanfattning : The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. LÄS MER

  3. 27. Mechanosensitive transcriptional regulation of gene expression in smooth muscle. Implications for health and disease

    Författare :Fatima Daoud; Molekylär kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle cell; phenotypic modulation; Yap Taz; MRTFA; hypertension; atherosclerosis;

    Sammanfattning : Smooth muscle participates in forming the wall of hollow organs, tracts, and blood vessels. Therefore, it plays a critical role in mediating vital functions in the body including regulation of blood pressure. LÄS MER

  4. 28. Developmental regulation of smooth muscle contraction in the urinary bladder

    Författare :Mari Ekman; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; newborn; Rho-kinase; cellular signaling; muscarinic receptors; calcium sensitivity; protein kinase C; non-muscle myosin; myosin light chain phosphatase;

    Sammanfattning : Smooth muscle cells in the urinary bladder are involved in the control of urine filling and emptying. We have used mice to study the contractile regulation of urinary bladder smooth muscle during the fetal period. LÄS MER

  5. 29. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways

    Författare :Cecilia Lövdahl; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metalloproteinase; extracellular matrix; ERK1 2 signalling; migration; proliferation; injury; vessel wall; smooth muscle cell; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. LÄS MER

  7. 30. Inducible nitric oxide synthase : in vascular smooth muscle cells

    Författare :Zhong-qun Yan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :nitric oxide; nitric oxide synthase; vascular smooth muscle cells; transcriptional regulation; NF-[kappa]B; I[kappa]B; pathophysiological role;

    Sammanfattning : Besides the constitutively expressed nitric oxide synthase (NOS) in endothelial cells, vascular smooth muscle cells (SMC) have the potential to express the inducible isoform of NOS (iNOS). Given the important effects of nitric oxide and the high output of this enzyme, expression of iNOS in SMC and its pathophysiological significance were investigated in the present study. LÄS MER