Sökning: "vascular smooth muscle"

Visar resultat 1 - 5 av 185 avhandlingar innehållade orden vascular smooth muscle.

  1. 1. Integration of signalling in smooth muscle caveolae

    Författare :Yulia Shakirova; Cellulär biomekanik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveola; caveolin; detrusor; cavin; smooth muscle contractility; remodelling; NO; vascular dysfunction; smooth muscle; erectile dysfunction;

    Sammanfattning : Caveolae and lipid rafts are plasma membrane microdomains that are considered to play a role in cellular signalling. Caveolins and cavins as well as cholesterol are required for the structure and function of caveolae. The papers summarized in this thesis examine the role of caveolae in smooth muscle function. LÄS MER

  2. 2. Transcriptome analysis on in vivo derived laser microbeam microdissected cells. Analysis of smooth muscle transcriptomes

    Författare :Stefan Johannes Scheidl; Göteborgs universitet; []
    Nyckelord :microarray; laser microdissection; RNA amplification; smooth muscle cells; smooth muscle differentiation; smooth muscle transcriptome; smooth muscle diversity;

    Sammanfattning : Smooth muscle cells (SMCs) are found in the respiratory, urogenital, circulatory and digestive systems. They provide contractility and structural support for those organs and perform multiple physiological important functions, such as modulation of blood pressure, regulation of airway resistance, and control of gastrointestinal and genitourinary motility. LÄS MER

  3. 3. Regulation of the vascular smooth muscle cell phenotype

    Författare :Henrik Lindskog; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryonic stem cells; vascular smooth muscle cell; smooth muscle cell; pericyte; phenotypic modulation; lipoma preferred partner; ectra-cellular matrix; zinc finger protein 148;

    Sammanfattning : Smooth muscle cells (SMC) are present in many internal organs such as the blood vessels and the gastrointestinal channel. Their main functions are to provide stability to the tissue and to provide contractile capability. SMC are not terminally differentiated but can switch between several phenotypes, which is also known as phenotypic modulation. LÄS MER

  4. 4. Dynamics of Ca2 handling in vascular smooth muscle

    Författare :Karl Dreja; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; phenotypic modulation; caveolae; Physiology; confocal microscopy; calcium; Fysiologi;

    Sammanfattning : Intracellular Ca2+ is a key regulator of vascular contractility, and thereby of blood perfusion and pressure. Ca2+ signals are essential also for cell migration, proliferation and regulation of numerous enzymes. LÄS MER

  5. 5. Phenotypic modulation of vascular smooth muscle in organ culture

    Författare :Anders Lindqvist; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; proliferation; PDGF; Physiology; energy metabolism; calcium; Fysiologi;

    Sammanfattning : Contraction of blood vessels for the regulation of blood flow and pressure is dependent on vascular smooth muscle cells (VSMC) located in the medial layer of the vascular wall. Adult, differentiated VSMC have a well developed contractile system and a low rate of proliferation. LÄS MER