Sökning: "non-muscle myosin"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden non-muscle myosin.
1. Variability and adaptation in the contractile system of smooth muscle
Sammanfattning : This thesis examines the cellular and molecular mechanisms involved in the large diversity of the contractile properties in smooth muscle. Six studies, I-VI, are included. I: a slow smooth muscle (aorta) has a different nucleotide and phosphate dependence compared to a fast type (taenia coli). LÄS MER
2. Developmental regulation of smooth muscle contraction in the urinary bladder
Sammanfattning : Smooth muscle cells in the urinary bladder are involved in the control of urine filling and emptying. We have used mice to study the contractile regulation of urinary bladder smooth muscle during the fetal period. LÄS MER
3. Function of contractile and cytoskeletal proteins in smooth muscle: Effects of hypertrophy and age and desmin removal in a transgenic animal
Sammanfattning : In man, the urinary bladder responds to an urinary outflow obstruction with a pronounced dilatation and growth of the bladder wall. This clinical situation can be mimicked in rat by creation of a partial urinary outflow obstruction and the papers included in the present thesis use this animal model to address questions regarding the adaptive changes in the smooth muscle of the growing bladder. LÄS MER
4. Molecular and microscopical analysis of pathogenic streptococci - studies on surface proteins interacting with human cells and extracellular matrix
Sammanfattning : Association to specific host tissue structures allows pathogenic bacteria to establish an infection and facilitates the spread within its host. Interactions between bacterial surface structures and human proteins might determine the outcome of the infection. Streptococcus pyogenes (S. LÄS MER
5. Cell motility : the organization of the microfilament system in cultured cells with special emphasis on the cortical weave of actin filaments
Sammanfattning : The microfilament system formed by actin, myosin and associated proteins constitutes the molecular basis for many of the motile phenomena which eukaryotic cells express. The organization of this system varies considerably from cell type to cell type, and is characterized on one hand by strictly ordered, more or less flexible arrangements of actin filaments and on the other by actin present in primarily a nonfilamentous form ready to polymerize in response to certain stimuli. LÄS MER