Sökning: "Smooth muscle"

Visar resultat 6 - 10 av 352 avhandlingar innehållade orden Smooth muscle.

  1. 6. Variability and adaptation in the contractile system of smooth muscle

    Författare :Mia Löfgren; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; essential light chain; desmin; shortening velocity; integrin; intermediate filament; hypertrophy; non-muscle myosin; smooth muscle; myosin; heavy chain; Physiology; Fysiologi;

    Sammanfattning : This thesis examines the cellular and molecular mechanisms involved in the large diversity of the contractile properties in smooth muscle. Six studies, I-VI, are included. I: a slow smooth muscle (aorta) has a different nucleotide and phosphate dependence compared to a fast type (taenia coli). LÄS MER

  3. 7. Dynamics of Ca2 handling in vascular smooth muscle

    Författare :Karl Dreja; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; phenotypic modulation; caveolae; Physiology; confocal microscopy; calcium; Fysiologi;

    Sammanfattning : Intracellular Ca2+ is a key regulator of vascular contractility, and thereby of blood perfusion and pressure. Ca2+ signals are essential also for cell migration, proliferation and regulation of numerous enzymes. LÄS MER

  4. 8. Modulaton of gene expression in human aortic smooth muscle cells by Porphyromonas gingivalis : a possible association between periodontitis and atherosclerosis

    Författare :Boxi Zhang; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Julia Davies; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microarray; Angiopoietin; Smooth muscle cells; TNF; Periodontitis; Atherosclerosis; Porphyromonas gingivalis; Cancer; Inflammasome; Biomedicin; Biomedicine;

    Sammanfattning : Porphyromonas gingivalis is a gram-negative, rod-shaped, and anaerobic bacterium that is involved in the pathogenesis of periodontitis. P. gingivalis produces a variety of virulence factors including gingipains and fimbriae. LÄS MER

  5. 9. Signal transduction and calcium sensitivity of smooth muscle contraction

    Författare :Johan Bonnevier; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; hypertrophy; CPI-17; MYPT1; myosin phosphatase; Rho kinase; PKC; smooth muscle; cGK;

    Sammanfattning : Smooth muscles are components of several physiologically important organs and often involved in disease. Smooth muscle contraction is regulated by variations in intracellular [Ca2+]; increased levels activate the myosin light chain kinase (MLCK) which phosphorylates myosin and initiates contraction. LÄS MER

  7. 10. Phenotypic modulation of vascular smooth muscle in organ culture

    Författare :Anders Lindqvist; Islet cell physiology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; proliferation; PDGF; Physiology; energy metabolism; calcium; Fysiologi;

    Sammanfattning : Contraction of blood vessels for the regulation of blood flow and pressure is dependent on vascular smooth muscle cells (VSMC) located in the medial layer of the vascular wall. Adult, differentiated VSMC have a well developed contractile system and a low rate of proliferation. LÄS MER