Sökning: "Reumatologi och molekylär skelettbiologi"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden Reumatologi och molekylär skelettbiologi.

  1. 1. Proteomics of the human meniscus in health and osteoarthritis

    Författare :Elin Folkesson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Knee; OSTEOARTHRITIS; Knee; Meniscus; PROTEOMICS; microstructure; articular cartilage;

    Sammanfattning : Introduction: Osteoarthritis (OA) is one of the most common causes of knee pain, and the most common form ofarthritis. It causes pain and disability, and there is currently no cure. Recent research in knee OA highlights therole of the meniscus in OA pathology. LÄS MER

  3. 2. Rheumatoid Arthritis in a 10-Year Perspective, Outcome for Patients Followed from Early Disease

    Författare :Elisabet Lindqvist; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; rheumatology locomotion; Skelett; COMP; Skeleton; muscle system; Anti-IL-1alpha; Anti-CCP; Rheumatoid factor isotypes; Mortality; Radiographic progression; Joint damage; Disease activity; HAQ; SOFI; Disability; Prognosis; Rheumatoid arthritis; Outcome;

    Sammanfattning : Rheumatoid arthritis (RA) is characterized by persistent inflammation, progressive joint damage and disability. This thesis describes the outcome after 10 years in a cohort of 183 RA patients (116 women, 67 men) recruited 1985-89. The mean age was 51 years and symptom duration 11 months at inclusion. LÄS MER

  4. 3. Joint disease biomarkers - discovery and application

    Författare :Dovilė Sinkevičiūtė; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Psoriatic arthritis; cartilage; Proteomics; Biomarkers; ELISA; Tissue culture; Extracellular matrix ECM ;

    Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER

  5. 4. Chronic musculoskeletal pain: a multifactorial process

    Författare :Stefan Bergman; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; widespread; SF-36; risk factors; rheumatoid arthritis; pain; musculoskeletal; epidemiology; fibromyalgia; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Sammanfattning : The aim was to study prevalence, assessment methods, and risk factors of chronic musculoskeletal pain, as well as effects on health status in a general population setting. A postal survey to a representative sample of 3928 subjects aged 20–74 years in 2 municipalities on the west coast of Sweden was followed by clinical examinations of selected subjects, and a three-year follow up survey to 2425 subjects who answered completely to the first. LÄS MER

  7. 5. Skin fibrosis, internal organ involvement and auto antibodies in systemic sclerosis: longitudinal development and impact on survival

    Författare :Roger Hesselstrand; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; proteoglycan; pulmonary hypertension; organ involvement; auto antibodies; survival; systemic sclerosis; prognosis;

    Sammanfattning : Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. LÄS MER