Sökning: "Smooth muscle"

Visar resultat 36 - 40 av 352 avhandlingar innehållade orden Smooth muscle.

  1. 36. Regulation of striated muscle contraction

    Författare :Ying Dou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background and Aims: Muscle contraction involves cross-bridge interaction between actin and myosin filaments, which is regulated by variations of intracellular [Ca2+] and influenced by several external control systems. To characterize the mechanism of contraction, we have studied the effects of pharmacological compounds influencing the actin-myosin interaction and/or Ca2+ activation systems. LÄS MER

  3. 37. On angiotensin II receptor type 2 receptors in the small intestine

    Författare :Sara Ewert; Göteborgs universitet; []
    Nyckelord :renin-angiotensin; angiotensin; small intestine; mucosa; epithelium; AT1; AT2; bradykinin; BK2 receptor; nitric oxide; iNOS; smooth muscle; contractility;

    Sammanfattning : The endocrine renin-angiotensin system (RAS) is important in the regulation of extracellular fluid volume and systemic blood pressure in strenuous conditions such as hypovolemia. Also present locally in peripheral tissues, all components of RAS are expressed and have been shown to modulate development, cell growth and inflammation. LÄS MER

  4. 38. Experimental Bladder Reconstruction

    Författare :Hans Frederiksen; Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; smooth muscle; detrusor; matrix; nerves; subtotal cystectomy; bladder regeneration; enterocystoplasty; nephrology; Urologi; nefrologi;

    Sammanfattning : Reduced urinary bladder capacity is a clinically significant problem. The surgical methods that have been available to treat this, such as urinary diversion or surgically augmenting the bladder by incorporation of intestinal segments, all have serious drawbacks. LÄS MER

  5. 39. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

    Författare :Sebastian Albinsson; Kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; cytochemistry; histochemistry; wall stress; shear stress; hypertension; Histology; differentiation; growth; caveolin; smooth muscle; actin; Fysiologi; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER

  7. 40. Interactions between mast cells and smooth muscle in asthma models

    Författare :Lisa Sjöberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergic asthma is the major phenotype of asthma and is characterized by specific responses to allergens as well as airway hyperresponsiveness (AHR), inflammation and remodelling. Mast cells and airway smooth muscle cells (ASM) play an important role in the allergic airway response and there are several indications that a cross-talk exists between these two cell types contributing to asthma pathogenesis. LÄS MER