Sökning: "metalloproteinase"

Visar resultat 1 - 5 av 96 avhandlingar innehållade ordet metalloproteinase.

  1. 1. Biomolecular Aspects of Flexor Tendon Healing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maria Berglund; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Flexor tendon healing; Growth factor; Metalloproteinase; Collagen; Proteoglycan; Myofibroblast; Hyaluronan synthase; Mast cell; MEDICINE Surgery Surgical research Hand surgery; MEDICIN Kirurgi Kirurgisk forskning Handkirurgi; Orthopaedics; Ortopedi;

    Sammanfattning : Flexor tendon injuries in zone II of the hand (i.e. between the distal volar crease and the distal interphalangeal joint) can be costly for both the afflicted individual and society because of the high cost of a long rehabilitation period, complicated by tendon ruptures or scarring with adhesion formation, causing impaired range of motion. LÄS MER

  2. 2. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways

    Detta är en avhandling från Cecilia Lövdahl, Dept of Cell and Molecular Biology, Section for Connective Tissue Biology, Lund University P.O Box 94, 221 00 Lund, SWEDEN

    Författare :Cecilia Lövdahl; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metalloproteinase; extracellular matrix; ERK1 2 signalling; migration; proliferation; injury; vessel wall; smooth muscle cell; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. LÄS MER

  3. 3. Impact of autocrine factors on physiology and productivity in Trichoplusia ni serum-free cultures

    Detta är en avhandling från Stockholm : KTH

    Författare :Ulrika Eriksson; KTH.; [2005]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Trichoplusia ni; High Five; insect cells; BEVS; serum-free medium; yeast extract; conditioned medium; autocrine regulation of proliferation; growth factors; cell cycle; metalloproteinase; specific productivity; Bioteknik; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Sammanfattning : The aim of this study was to increase the understanding of the mechanisms regulating cell proliferation and recombinant protein production in serum-free cultures of Trichoplusia ni (T. ni) insect cells.Conditioned medium (CM) was shown to contain both stimulatory and inhibitory factors (CM factors) influencing cell growth. LÄS MER

  4. 4. Towards surgical use of matrix metalloproteinase biology

    Detta är en avhandling från Linköping University Electronic Press

    Författare :Björn Pasternak; Per Aspenberg; Pentti Tengvall; Yrjö T Konttinen; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; colon; tetracyclines; tissue inhibitor of metalloproteinases TIMP ; wound healing.; colorectal surgery; extracellular matrix; humans; matrix metalloproteinases MMPs ; rats; surgical anastomosis; sutures; tendon injuries; MEDICINE Surgery Surgical research Orthopaedics; MEDICIN Kirurgi Kirurgisk forskning Ortopedi;

    Sammanfattning : Matrix metalloproteinases (MMPs), such as collagenases, are a family of enzymes capable of degrading most constituents of the extracellular matrix. MMPs are thought to be involved in the aetiopathogenesis of tendon rupture. Additionally, failure of healing has in some instances been associated with elevated levels of MMPs. LÄS MER

  5. 5. Skeletal muscle matrix metalloproteinase and exercise in humans

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Laboratory Medicine

    Författare :Eric Rullman; Karolinska Institutet.; Karolinska Institutet.; [2011]

    Sammanfattning : Skeletal muscle is a highly plastic tissue; it has a great capacity to adapt to environmental demands throughout life. The structural and functional changes that occur in response to exercise training are well characterized whereas much less is known about these adaptive processes at the cellular and molecular levels. LÄS MER