Sökning: "phenotypic modulation"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden phenotypic modulation.

  1. 1. Hypoxia-induced phenotypic modulation of human neuroblastoma cells

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Linda Holmquist Mengelbier; Lund University.; Lunds universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; reoxygenation; HIF-2a; HIF-1a; differentiation; hypoxia; neuroblastoma;

    Sammanfattning : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. LÄS MER

  2. 2. Phenotypic modulation of vascular smooth muscle in organ culture

    Detta är en avhandling från BMC Biomedical Centre, Lund University

    Författare :Anders Lindqvist; Lund University.; Lunds universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; proliferation; PDGF; Physiology; energy metabolism; calcium; Fysiologi;

    Sammanfattning : Contraction of blood vessels for the regulation of blood flow and pressure is dependent on vascular smooth muscle cells (VSMC) located in the medial layer of the vascular wall. Adult, differentiated VSMC have a well developed contractile system and a low rate of proliferation. LÄS MER

  3. 3. Dynamics of Ca2 handling in vascular smooth muscle

    Detta är en avhandling från BMC Biomedical Centre, Lund University

    Författare :Karl Dreja; Lund University.; Lunds universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; phenotypic modulation; caveolae; Physiology; confocal microscopy; calcium; Fysiologi;

    Sammanfattning : Intracellular Ca2+ is a key regulator of vascular contractility, and thereby of blood perfusion and pressure. Ca2+ signals are essential also for cell migration, proliferation and regulation of numerous enzymes. LÄS MER

  4. 4. Regulation of the vascular smooth muscle cell phenotype

    Detta är en avhandling från BMC Biomedical Centre, Lund University

    Författare :Henrik Lindskog; Göteborgs universitet.; Gothenburg University.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryonic stem cells; vascular smooth muscle cell; smooth muscle cell; pericyte; phenotypic modulation; lipoma preferred partner; ectra-cellular matrix; zinc finger protein 148;

    Sammanfattning : Smooth muscle cells (SMC) are present in many internal organs such as the blood vessels and the gastrointestinal channel. Their main functions are to provide stability to the tissue and to provide contractile capability. SMC are not terminally differentiated but can switch between several phenotypes, which is also known as phenotypic modulation. LÄS MER

  5. 5. Mesenchymal stromal/stem cells : Expansion, engraftment and immune modulation

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Laboratory Medicine

    Författare :Håkan Samuelsson; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Due to their production of hematopoietic growth factors and their immunomodulatory capacity, bone marrow-derived mesenchymal stromal/stem cells (MSC), are a promising tool in the procedure of hematopoietic stem cell transplantation (HSCT). Seven patients undergoing allogeneic HSCT were co-infused with MSC. LÄS MER