Sökning: "Adiponectin"

Visar resultat 21 - 25 av 73 avhandlingar innehållade ordet Adiponectin.

  1. 21. Membrane Fluidity Regulation: From C. elegans to mammalian cells

    Författare :Ranjan Devkota; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR-2; adiponectin receptors; IGLR-2; saturated fats; membrane fluidity; fatty acid desaturation; unsaturated fatty acid; membrane homeostasis;

    Sammanfattning : Biological membranes are primarily an assembly of lipids and proteins. Collectively, these constituents within a phospholipid bilayer determine the physical membrane properties such as fluidity, viscosity, thickness, packing and permeability. Maintenance of membrane properties within acceptable margins, i.e. LÄS MER

  2. 22. Genetic predisposition and dietary factors in relation to adiponectin and insulin resistance

    Författare :He Gao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes mellitus is a global health problem, owing to the high prevalence and enormous associated economic burden. Insulin resistance is a critical condition to the development of type 2 diabetes (T2D). Adiponectin, a hormone secreted by the adipose cells, has attracted much attention for its insulin-sensitizing and anti-diabetic effects. LÄS MER

  3. 23. Angiogenesis in obesity and cancer

    Författare :Ebba Bråkenhielm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adiponectin; endothelial cells; Leptin; Resveratrol; TNP-470;

    Sammanfattning : Angiogenesis is the process of blood vessel growth from pre-existing vasculatures. In the adult, it is involved in certain physiological processes, such as in organ and tissue regeneration, wound healing, and in female reproductive cycles. LÄS MER

  4. 24. Angiostatic mechanisms of endogenous angiogenesis inhibitors

    Författare :Niina Veitonmäki; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiogenesis; tumor growth; angiostatin; K 1 - 5; adiponectin; hTERT; p16;

    Sammanfattning : Angiogenesis, the process of sprouting of new capillaries from the existing blood vessels, is essential for tumor growth and metastasis. Angiostatin was discovered as the first specific endogenous angiogenesis inhibitor nearly 10 years ago. The structure of angiostatin consists of the first three/four kringle (K1-3/K1-4) domains of plasminogen. LÄS MER

  5. 25. On endothelial function in type 2 diabetic patients with coronary artery disease

    Författare :Thomas Nyström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes; endothelial dysfunction; insulin resistance; coronary artery disease; nitric oxide; glucagon-like peptide 1; exendin; tetrahydrobiopterin; inflammation; adiponectin; resistin; C-reactive protein; tumor necrosis factor a; interleukin-6;

    Sammanfattning : Patients with type 2 diabetes have a poor outcome suffering a myocardial infarction (MI). Endothelial dysfunction may play a role in this poor prognosis. In type 2 diabetes, endothelial dysfunction is a salient feature coexisting with obesity and insulin resistance and may be linked by the same pathophysiology, i.e. LÄS MER