Sökning: "IGLR-2"

Hittade 3 avhandlingar innehållade ordet IGLR-2.

1. 1. Membrane Fluidity Regulation: From C. elegans to mammalian cells

   Författare :Ranjan Devkota; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR-2; adiponectin receptors; IGLR-2; saturated fats; membrane fluidity; fatty acid desaturation; unsaturated fatty acid; membrane homeostasis;

   Sammanfattning : Biological membranes are primarily an assembly of lipids and proteins. Collectively, these constituents within a phospholipid bilayer determine the physical membrane properties such as fluidity, viscosity, thickness, packing and permeability. Maintenance of membrane properties within acceptable margins, i.e. LÄS MER

3. 2. C. elegans PAQR-2 ‒ A Regulator of Membrane Homeostasis

   Författare :Emma Svensk; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRRIG; glucose; membrane fluidity; desaturase; homeoviscous adaptation;

   Sammanfattning : The progestin and adipoQ receptor (PAQR) protein family is characterized by a 7-transmembrane domain, and a topology reversed that of G-protein coupled receptors, i.e. the N-terminus resides in the cytoplasm. LÄS MER

4. 3. Regulators of Membrane Fluidity

   Författare :Kiran Busayavalasa; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRIG; membrane fluidity;

   Sammanfattning : Caenorhabditis elegans PAQR-2 (a homolog of the mammalian AdipoR1 and AdipoR2 proteins) and IGLR-2 (homolog of the mammalian LRIG proteins) form a complex at the plasma membrane that regulates fatty acid desaturation to protect against saturated fatty acid-induced membrane rigidification. Maintenance of membrane homeostasis is fundamental for most cellular processes and, given its importance, robust regulatory mechanisms must exist that adjust lipid composition to compensate for dietary variation. LÄS MER