Sökning: "Ebba Bråkenhielm"

Hittade 2 avhandlingar innehållade orden Ebba Bråkenhielm.

1. 1. Angiogenesis in obesity and cancer

   Författare :Ebba Bråkenhielm; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adiponectin; endothelial cells; Leptin; Resveratrol; TNP-470;

   Sammanfattning : Angiogenesis is the process of blood vessel growth from pre-existing vasculatures. In the adult, it is involved in certain physiological processes, such as in organ and tissue regeneration, wound healing, and in female reproductive cycles. LÄS MER

3. 2. Cell-autonomous and paracrine mechanisms underlying Pik3ca-driven vascular malformations

   Författare :Milena Petkova; Taija Mäkinen; Ebba Bråkenhielm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PI3K; PI3KCA; lymphatic malformations; H1047R;

   Sammanfattning : Vascular malformation is a benign overgrowth of blood or lymphatic vessels leading to life-threatening consequences for affected patients. Activating mutations in the TIE2 receptor cause the majority of venous malformations (VMs), while somatic activating mutations in PIK3CA, leading to the overactivation of the PI3K-AKT pathway, cause both VMs and lymphatic malformations (LMs). LÄS MER