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Visar resultat 1 - 5 av 73 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Adiponectin in atherosclerosis

    Författare :Jonas Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adiponectin;

    Sammanfattning : Adiponectin is a protein secreted from adipocytes, circulating at high levels in plasma (3 30μg/mL), and in overweight subjects it is down regulated. Adiponectin inhibits the development of atherosclerosis in experimental animal models but whether adiponectin is anti atherogenic in humans is not known. LÄS MER

  3. 2. Adiponectin : genetic determinants and relations with subclinical cardiovascular disease

    Författare :Stefan Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adiponectin;

    Sammanfattning : Cardiovascular disease (CVD) is a major cause of morbidity and premature death in Sweden and globally, which besides the substantial individual suffering, puts large restraints on the public health system. Adiponectin is a highly heritable trait, which is strongly associated with metabolic disturbances such as obesity and insulin resistance. LÄS MER

  4. 3. Adiponectin, the metabolic syndrome and atherosclerosis. Observation and intervention studies

    Författare :Carl Johan Behre; Göteborgs universitet; []
    Nyckelord :Adiponectin; inflammation; obesity; weight loss; insulin resistance; the metabolic syndrome; diabetes mellitus type 2; atherosclerosis; ultrasound;

    Sammanfattning : .... LÄS MER

  5. 4. Adipocyte-derived hormones and cardiovascular disease

    Författare :Maria Eriksson; Stefan Söderberg; Tommy Olsson; Lena Jonasson; Umeå universitet; []
    Nyckelord :leptin; adiponectin; fibrinolysis; vWF; myocardial infarction; sex differences; physical activity; risk factors;

    Sammanfattning : Obesity is increasing globally and related to major changes in lifestyle. This increase is associated with an increased risk of cardiovascular disease (CVD). Knowledge about adipose tissue as a metabolic-endocrine organ has increased during the last few decades. LÄS MER

  7. 5. Effects of cytokines on preadipocyte differentiation and Wnt signalling

    Författare :Birgit Gustafson; Göteborgs universitet; []
    Nyckelord :adipocyte differentiation; adiponectin; beta-Catenin; C EBPalpha; IL-6; PPARgamma; TNFalpha; Wnt signalling;

    Sammanfattning : The relationship between amount of adipose tissue, the Metabolic Syndrome and Type 2 diabetes has been recognized for several years. However, the mechanisms for this remain to be clarified. Not all obese individuals develop insulin resistance or Type 2 diabetes and these perturbations are also seen in non-obese individuals. LÄS MER