Sökning: "fatty acid desaturation"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden fatty acid desaturation.

  1. 1. Sources of Arachidonic Acid in Platelets, Bone, Marrow and Gastrointestinal Tract

    Författare :Li Zhou; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phospholipids; Megakaryocyte; Lysophosphatidylcholine; Lipoproteins; Linoleic acid; Intralipid; Interconversion; Gastrointestinal tract; Plasma free fatty acids; Fasting; Dietary fatty acids; Desaturase; Cholesterol; Chylomicron remnant; Chylomicron; Arachidonic acid; Bone marrow; Platelets; Protein S; Prothrombin; Triglycerides.; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : This study investigates pathways by which the eicosanoid precursor pools in the platelets, bone marrow and the gastrointestinal (GI) mucosa are acquired and regulated, and in this context some aspects on the interaction between triglyceride (TG)-rich lipoproteins and platelets. 1. LÄS MER

  2. 2. Membrane Fluidity Regulation: From C. elegans to mammalian cells

    Författare :Ranjan Devkota; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR-2; adiponectin receptors; IGLR-2; saturated fats; membrane fluidity; fatty acid desaturation; unsaturated fatty acid; membrane homeostasis;

    Sammanfattning : Biological membranes are primarily an assembly of lipids and proteins. Collectively, these constituents within a phospholipid bilayer determine the physical membrane properties such as fluidity, viscosity, thickness, packing and permeability. Maintenance of membrane properties within acceptable margins, i.e. LÄS MER

  3. 3. Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease : Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat

    Författare :Eva Warensjö; Ulf Risérus; Bengt Vessby; Tommy Cederholm; David Laaksonen; Uppsala universitet; []
    Nyckelord :Nutrition; Fatty acids; Dietary fat; Biomarker; Metabolic Syndrome; Mortality; Obesity; Insulin Sensitivity; Epidemiology; Estimated desaturase activities; Stearoyl-CoA-desaturase; delta-6-desaturase; delta-5-desaturase; Single Nucleotide Polymorphism; Dietary Intervention; Rapeseed oil; Saturated fat; SCD1; Näringslära;

    Sammanfattning : The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. LÄS MER

  4. 4. On the way of making plants smell like moths - a synthetic biology approach

    Författare :Bao-Jian Ding; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; moth pheromone; transcriptome; fatty acyl desaturase; fatty acyl reductase; acetyltransferase; chain shortening; chain elongation; heterologous expression; synthetic biology; plant expression;

    Sammanfattning : Moth caterpillars are major agricultural pests in many parts of the world. In general female moths attract male mates with their pheromone over long distance. Most of the described moth pheromones belong to the same class of chemical compounds, fatty acid derivatives that are produced de novo in the pheromone gland. LÄS MER

  5. 5. Crystallographic studies of enzymes involved in biosynthesis of fatty acids : beta-ketoacyl-acyl carrier protein synthase II and delta9-stearoyl-ACP desaturase

    Författare :Martin Moche; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the biosynthesis of fatty acids, the beta-Ketoacyl Acyl Carrier Protein Synthases (Kas) catalyse chain elongation by the addition of two-carbon units derived from malonyl-ACP, to an acyl group bound to CoA or the small protein ACP. These enzymes are potential targets for antibiotics against bacterial or parasitical infections and their mammalian counterparts could hopefully be used as drug targets against certain cancers and obesity. LÄS MER