Sökning: "translation control"

Visar resultat 6 - 10 av 158 avhandlingar innehållade orden translation control.

  1. 6. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

    Författare :Marcus Sokolowski; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER

  3. 7. Att spränga normer : om målstyrningsprocesser för jämställdhetsintegrering

    Författare :Eva Wittbom; Kaj Sköldberg; Lillemor Westerberg; Ulla Eriksson-Zetterquist; Stockholms universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Management control; management by objectives; gender perspective; gender mainstreaming; institutional theory; loose coupling; translation; interpretive approach; case study; central government; public transport sector; ekonomistyrning; målstyrning; genusperspektiv; jämställdhetsintegrering; genusintegrering; institutionell teori; lösa kopplingar; översättning; tolkande ansats; fallstudie; statlig styrning; offentlig transportsektor; Business studies; Företagsekonomi; företagsekonomi; Business Administration;

    Sammanfattning : How do management control systems function when under pressure to mainstream gender equality into a core business? This question is being discussed with an interpretive approach from both the institutional and the gender perspective. Empirical evidence stems from two longitudinal case studies within the Swedish public sector where management by objectives (MBO) is the current model for governmental control. LÄS MER

  4. 8. Sagittal plane knee translation in healthy and ACL deficient subjects : a methodological study in vivo with clinical implications

    Författare :Anil Vergis; Jon Karlsson; Linköpings universitet; []
    Nyckelord :anterior cruciate ligament; electrogoniometer system; gait; knee; kinematics; motion analysis; step ascent; step descent; translation; MEDICINE; MEDICIN;

    Sammanfattning : This study on human subjects, comprises of four cross sectional and one prospective cohort study. The general purpose of this work was to develop a technique for measuring in vivo, sagittal anterior-posterior translatory motions in the knee joint using a computerized electrogoniometer (CA-4000, OS Inc., Hayward CA, USA). LÄS MER

  5. 9. Computational Studies of Protein Synthesis on the Ribosome and Ligand Binding to Riboswitches

    Författare :Christoffer Lind; Johan Åqvist; Alexander MacKerell Jr; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Binding free energy; Ribosome; Codon reading; Translation initiation; Translation termination; Mitochondrial translation; Release factor; Purine riboswitch; Molecular Dynamics; Free Energy Perturbation; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : The ribosome is a macromolecular machine that produces proteins in all kingdoms of life. The proteins, in turn, control the biochemical processes within the cell. It is thus of extreme importance that the machine that makes the proteins works with high precision. LÄS MER

  7. 10. RNA modifications and post-transcriptional control in cancer and stem cells

    Författare :Giulia Beneventi; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; Pseudouridine; 2’-O-methylation; Splicing; Translation; non-coding RNAs; Cancer; Stem cells; Differentiation; Stress response;

    Sammanfattning : Splicing and translation are two of the key steps of post-transcriptional regulation of gene expression. Their tight regulation is essential for development, whereas their deregulation is involved in cancer pathogenesis. Nevertheless, many of the molecular mechanisms controlling these processes are still unknown. LÄS MER