Sökning: "Biokemi"
Visar resultat 1 - 5 av 2016 avhandlingar innehållade ordet Biokemi.
1. Interpreting a Giant Studies of Structure and Function of Tripeptidyl-peptidase II
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Tripeptidyl-peptidase II (TPP II) is a subtilisin-like serine peptidase that forms a gigantic homooligomeric complex, and is involved in the degradation of peptides in the cytosol. In addition, TPP II has been implicated in specific cellular processes, such as apoptosis control and adipogenesis, but if this is dependent on its endo- or exopeptidase activity remains to be determined. LÄS MER
2. Directed Evolution of Glutathione Transferases with Altered Substrate Selectivity Profiles A Laboratory Evolution Study Shedding Light on the Multidimensional Nature of Epistasis
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Directed evolution is generally regarded as a useful approach in protein engineering. By subjecting members of a mutant library to the power of Darwinian evolution, desired protein properties are obtained. Numerous reports have appeared in the literature showing the success of tailoring proteins for various applications by this method. LÄS MER
3. Structural studies on the integral membrane protein, ubiquinol oxidase from Escherichia coli
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Heme-copper oxidases are redox-driven proton pumps that couple the reduction of molecular oxygen to water with the vectorial translocation of protons across the membrane. The proton gradient generated by heme-copper oxidases and the other members of the aerobic respiratory chain is ultimately used to drive the synthesis of ATP. LÄS MER
4. Partition chromatography of drugs on immobilized liposomes and biomembranes : A method applicable to screening in drug design
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : One of the main pathways for drug passage into cells is diffusion across the lipid bilayer ofthe cell membrane. A key factor in this process is the drug partitioning into the bilayer, whichcan be translated into a retention in a chromatographic system. LÄS MER
5. Multiple Functions of Glutathione Transferases A Study on Enzymatic Function, Regulatory Role and Distribution in Mouse and Man
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : To cope with various endogenous toxin and xenobiotics nature has equipped the organisms with a proper protection system. Glutathione transferases (GSTs) are important components of the cellular defense against oxidative stress. These proteins appear to be suited for different tasks. LÄS MER
