Sökning: "late genes"
Visar resultat 1 - 5 av 231 avhandlingar innehållade orden late genes.
1. Candidate Genes for Late Diabetic Complications
Sammanfattning : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. LÄS MER
2. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element
Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER
3. On the influence of dopamine-related genetic variation on dopamine-related disorders
Sammanfattning : Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are under the influence of numerous transcription and neurotrophic factors. LÄS MER
4. Investigating the impacts of Late Pleistocene climate change on Arctic mammals using palaeogenomics
Sammanfattning : The climatic fluctuations of the Late Pleistocene likely had a large impact on the evolutionary history of Arctic species. Palaeogenomics is a useful tool to shed light on how past populations responded to these climatic shifts and the associated ice sheet dynamics and sea level change. LÄS MER
5. Association studies on susceptibility genes in Alzheimer disease
Sammanfattning : Alzheimer disease (AD) is the most common form of dementia in the elderly. Due to the complexity of AD, it has been difficult to find genetic risk factors predisposing to disease. To date, three genes (APP, PSEN1 and PSEN2) with disease causing genetic variants have been reported for the rare early onset monogenic forms of AD. LÄS MER