Sökning: "HPV-1"

Hittade 4 avhandlingar innehållade ordet HPV-1.

1. 1. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

   Författare :Marcus Sokolowski; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER

3. 2. Posttranscriptional regulation of gene expression in retroviruses and human papillomaviruses

   Författare :Wei Tan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :CTE; EIAV; HIV- 1; HPV; Rev; RRE; splice site; SRV- 1; 3 UTR Stockholm 1996 Doctoral Thesis;

   Sammanfattning : Human immunodeficiency virus type I (HIV-1) is the prototype of complex retroviruses, whereas human papillomaviruses (HPVs) are nonenveloped, cricular double-stranded DNA viruses. The HIV-1 Rev protein is a posttranscriptional regulator, which acts on its target RNA sequence termed the Rev-responsive element (RRE) to facilitate nuclear export of unspliced and partially spliced HIV-1 mRNAs, and to improve their stability and translatability. LÄS MER

4. 3. Role of the 3'UTR in translation and stability of HCV and HPV mRNAs

   Författare :Lisa Wiklund; Laszlo Szekely; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hepatitis C virus; Human Papillomavirus; 3’ untranslated region; AU-rich sequence; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Virus mRNAs can be divided into functional regions. The focus of this thesis will be to investigate the function of one of these regions, the 3’ untranslated region (UTR). The 3’UTR of HCV contains a U-rich element and the late 3’UTR of HPV-1 contains an AU-rich element. LÄS MER

5. 4. Human papillomavirus in tonsillar cancer

   Författare :Hanna Mellin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Human papillomviruses (HPVs) are known to be causative agents for the development of cervical carcinoma. To what extent HPV is associated with head and neck cancer remains to be clarified, but an association to tonsillar cancer has been proposed. Importantly, the oncogenes of HPV-16, namely E6 and E7, are generally expressed in tonsillar cancer. LÄS MER