Sökning: "sinus mucosa"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden sinus mucosa.

  1. 1. Distribution and Effects of NO and CO in the Human Upper Respiratory Tract

    Författare :Jens Andersson; Helsingborg Kliniska Vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; transplantation; Microbiology; bacteriology; virology; serologi; Immunologi; serology; Otorhinolaryngology; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; Immunology; sinus; upper respiratory tract infection; nose; nitric oxide; neutrophil migration; middle ear; hemin; flow cytometry; allergy; carbon monoxide;

    Sammanfattning : Mucosal inflammation and airway hyperreactivity are regulated by hundreds of different mediators. The recent discovery of gaseous mediators, produced and active within the airways, opens new possibilities for identification of therapeutic targets and ways to monitor airway inflammation. LÄS MER

  2. 2. Aspects of the inflammatory response and formation of polys in the nasal and sinus mucosa

    Författare :Tomas Norlander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental sinusitis was induced in rabbits by ostial occlusion, with or without subsequent inoculation of Streptococcus pneumoniae, Staphylococcus aureus or Bacteroides fragilis The general inflammatory response, including goblet cell differentiation and polyp formation, was morphologically investigated. Polyps were experimentally induced by a combining mechanical trauma the mucosa with infection or by injection of agarose or N-formyl-methionyl-leucyl-phenylalanine (FMLP) into the maxillary sinus. LÄS MER

  3. 3. Mucosal regeneration following sinus surgery : an experimental study and clinical study

    Författare :Karin Forsgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :chronic sinusitis; histopathology; Caldwell-Luc operation; sinus surgery; rabbit; regeneration; sinus mucosa; experimental sinusitis; microcirculation; blood flow; vasoreactivity; nerve regeneration; sympathetic; neuropeptide Y; tyrosine hydroxylase; immunocytochemistry;

    Sammanfattning : The investigations described in this thesis concerned functional and structural aspects of the regenerated sinus mucosa following sinus surgery. In a biopsy material collected pre- and postoperatively from patients with chronic maxillary sinusitis, randomized for treatment with either Functional Endoscopic Sinus Surgery (FESS) or the Caldwell-Luc procedure (CL), histological parameters were evaluated semi-quantitatively and correlated to endoscopic findings and patients' symptoms. LÄS MER

  4. 4. Sensory neuropeptides and nitric oxide in nasal vascular regulation

    Författare :Johan Rinder; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Sensory nerves; neuropeptides; nasal mucosa; nitric oxide; vascular regulation; acoustic rhinometry; NK1-receptors; CGRP-receptors; vanilloid receptors; capsaicin; lactic acid; exercise; a-adrenoceptor agonists; pig; human.;

    Sammanfattning : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. LÄS MER

  5. 5. On Health-Related Quality of Life and Diagnostic Improvements in Rhinosinusitis

    Författare :Pernilla Sahlstrand Johnson; allergi och livskvalitet Laryngoesofagologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rhinosinusitis; nasal polyps; health-related quality of life; absenteeism; Doppler ultrasound; acoustic streaming; attenuation;

    Sammanfattning : Rhinosinusitis is defined as an inflammatory process involving the mucosa of the nose and one or more of the paranasal sinuses. The aims of the work presented in this thesis were to investigate the degree to which rhinosinusitis affects the health-related quality of life (HRQOL), and to determine whether the diagnosis of this condition can be improved using Doppler ultrasound. LÄS MER