Sökning: "NK1-receptors"
Hittade 4 avhandlingar innehållade ordet NK1-receptors.
1. Sensory neuropeptides and nitric oxide in nasal vascular regulation
Sammanfattning : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. LÄS MER
2. Positron Emission Tomography (PET) Studies in Anxiety Disorders
Sammanfattning : Anxiety disorders are very common and the primary feature is abnormal or inappropriate anxiety. Fear and anxiety is often mediated by the amygdala, a brain structure rich in substance P (SP) and neurokinin 1 (NK1) receptors. LÄS MER
3. Modulation by substance P in the lamprey spinal cord
Sammanfattning : Neuromodulation is a key element for animal adaptation to environmental circumstances. Neuromodulators can alter the output of a physiological system by acting on the motor circuit by transforming intrinsic firing properties and altering synaptic strength. Substance P belongs to the family of tachykinin, which are peptidergic neuromodulators. LÄS MER
4. 11C Molecular Imaging in Focal Epilepsy
Sammanfattning : Epilepsy is a common neurological disease affecting 6 million people in Europe. Early prevention and accurate diagnosis and treatment are of importance to obtain seizure freedom. In this thesis new applications of carbon-11-labelled tracers in PET and autoradiographic studies were explored in focal epilepsy. LÄS MER