Sökning: "oxidized LDL"

Visar resultat 1 - 5 av 47 avhandlingar innehållade orden oxidized LDL.

  1. 1. Regulation of human macrophage gene expression by oxidized low density lipoprotein. Studies on tumor necrosis factor-a and global gene expression profiles

    Detta är en avhandling från Göteborg

    Författare :Mikael C. O. Englund; Göteborgs universitet.; Gothenburg University.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; macrophage; gene expression; TNF-a; oxidized LDL; oxysterol; transcription factor; microarray;

    Sammanfattning : Atherosclerosis is a multifactorial and progressive disease that is characterized by a focal thickening of the arteries caused by accumulation of lipoproteins, extracellular matrix, and the migration and proliferation of various cell types. Among the cells found in atherosclerotic lesions are macrophages, which accumulate lipids and are transformed into foam cells. LÄS MER

  2. 2. Development of a Passive Immunization Strategy Against Atherosclerosis

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Alexandru Schiopu; Lunds universitet.; Lund University.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; regression; plaque; peptide; oxidized LDL; immune system; carotid stenosis; cardiovascular diseases; apolipoprotein B-100; atherosclerosis; Kardiovaskulära systemet; Cardiovascular system; vascular injury; ultrasound; antibodies;

    Sammanfattning : Popular Abstract in Swedish Åderförfettning (även kallat åderförkalkning eller ateroskleros) börjar genom att det ?onda kolesterolet? LDL fastnar i väggen på ett blodkärl. Där kan LDL börja modifieras och orsaka inflammation. Inflammationen påskyndas av att vita blodceller kommer in i artärväggen och försöker ta bort fettet. LÄS MER

  3. 3. Studies on effects of antioxidants on arterial thrombosis and endothelial cell injury : With special reference to Tocopherols and ApoA1 Milano

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Dayuan Li; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; tocopherols; apoA1 Milano; platelet aggregation; thrombosis; superoxide dismutase; nitric oxide synthase; endothelial cells; oxidized LDL; transcription factor; apoptosis; Kirurgi; MEDICINE Surgery; MEDICIN Kirurgi; rättsmedicin; Forensic Medicine;

    Sammanfattning : Coronary arterial endothelial injury and thrombosis are believed to be critical factors in the pathogenesis of coronary artery disease (CAD). Experimental studies have provided evidence for au inverse relation between acute coronary events and antioxidant intake. LÄS MER

  4. 4. Effects of hypoxia on macrophage function in atherosclerosis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ellen Knutsen Rydberg; Göteborgs universitet.; Gothenburg University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atherosclerosis; hypoxia; macrophage; IL-8; oxidized LDL; oxysterols; 15-lipoxygenase-2;

    Sammanfattning : Atherosclerosis is a complex disease, which affects large and medium sized arteries and is characterized by an arterial wall thickening. A constant supply of oxygen is needed to maintain cell functions in the atherosclerotic plaque. The oxygen distribution to the cells in the arterial wall depends on diffusion. LÄS MER

  5. 5. Lipids and Endothelium-Dependent Vasodilation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Peter Steer; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Atherosclerosis; endothelium; vasodilation; nitric oxide; fatty acid; meal; diet; lipoprotein; cyclooxygenase; diclophenac; L-arginine; LDL; human; Medicin; MEDICINE Dermatology and venerology; clinical genetics; internal medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Internal Medicine; Internmedicin;

    Sammanfattning : Impaired endothelium-dependent vasodilation (EDV) is associated with atherosclerotic cardiovascular disease as well as several of its risk factors.The aim of the present thesis was to investigate how lipids influence EDV in the vascular bed of the human forearm. LÄS MER