Sökning: "UCP"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet UCP.

1. 1. Candidate Genes for Late Diabetic Complications

   Författare :Eero Lindholm; diabetes och endokrinologi Genomik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF; sekretion; LTA; Endocrinology; nephropathy; diabetes mellitus; retinopathy; neuropathy; genetic; UCP; diabetologi; AGER; MHc2TA; HLA-DQB1; Endokrinologi; secreting systems; diabetology;

   Sammanfattning : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. LÄS MER

3. 2. Glucocorticoid administration : studies on weight regulation and metabolic implications

   Författare :Joanna Uddén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Glucocorticoids; leptin; obesity; adipose tissue; PAI-1; UCP-2; cortisol; the metabolic syndrome; 11 beta-HSD; eating behaviour; weight gain.;

   Sammanfattning : Long-term treatment with glucocorticoids induces weight gain and increased risk to develop obesity-related metabolic complications like insulin resistance, type 2 diabetes and cardiovascular disease. Glucocorticoids have been suggested to play a role in development of visceral fat accumulation. LÄS MER

4. 3. The pathophysiology of respiratory chain dysfunction

   Författare :José Pablo Silva; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondrial disease; mitochondrial DNA mtDNA ; mitochondrial transcription factor A Tfam ; Cre-loxP; conditional knockout; reactive oxygen species ROS ; superoxide; uncoupling protein UCP ; mitochondrial bioenergeties; energy expenditure;

   Sammanfattning : Mutations of mitochondrial DNA cause a variety of clinical syndromes. It is unclear whether impaired oxidative phosphorylation on its own is the main cause of pathology or whether other factors such as secondary metabolic alterations, enhanced formation of reactive oxygen species (ROS) and induction of apoptosis also may contribute to the clinical phenotype. LÄS MER

5. 4. Unexplained chest pain in men and women - symptom perception and outcome

   Författare :Annika Janson Fagring; Göteborgs universitet; []
   Nyckelord :Chest pain; unexplained chest pain; gender; daily life; psychosocial factors; stress; healthrelated quality of life;

   Sammanfattning : Patients with chest pain account for a large number of all patients seeking health care. The majority of these patients are referred to emergency departments (ED) and many of them are given a discharge diagnosis of unexplained chest pain (UCP). Our knowledge of this increasing number of patients with UCP is limited. LÄS MER

7. 5. Patients with unexplained chest pain ? Pain experience, stress, coping and health-related quality of life

   Författare :Margaretha Jerlock; Göteborgs universitet; []
   Nyckelord :chest pain; coping; illness; life events; nursing; quality of life; sleep; stress symptom;

   Sammanfattning : Chest pain is a common symptom that causes individuals to seek acute care at emergency departments; however, more than half of these patients are judged to have no organic cause to their pain. In Sweden, the number of patients discharged from hospital with a diagnosis of unexplained chest pain (UCP) has increased from 8,432 in 1987 to 17,555 in 2005. LÄS MER