Sökning: "repolarisation"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet repolarisation.

  1. 1. Autonomic function and myocardial repolarisation. Studies in renal diseases and in spinal cord injury

    Författare :Sinsia Gao; Göteborgs universitet; []
    Nyckelord :vagus; sympathetic nervous system; repolarisation; baroreflex; reproducibility; agreement; hypertension; spinal cord injury; autonomic dysreflexia; renal failure.;

    Sammanfattning : Both experimental and clinical evidence indicates that cardiac parasympathetic markers such as baroreflex sensitivity (BRS) and heart rate variability (HRV) have significant prognostic value. Furthermore, increased myocardial repolarisation lability reflected by increased QT variability index (QTVI) has been identified as a predictor for sudden cardiac death. LÄS MER

  2. 2. Cardiovascular assessment in middle-aged male long distance runners

    Författare :Philip Aagaard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :early repolarisation;

    Sammanfattning : Endurance events such as long distance running races are increasing in popularity and convey multiple health benefits. However, such exercise forms also represent a major challenge to human cardiovascular physiology and are associated with a momentarily increased risk for adverse cardiac events. LÄS MER

  3. 3. Cardiac effects of prolonged exercise

    Författare :Anders Sahlén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Angiotensin-Converting Enzyme; Exercise; Natriuretic Peptides; Troponin;

    Sammanfattning : Long-distance running is growing in popularity. While moderate exercise unquestionably gives major health benefits, the effects of extreme physical exhaustion on cardiac function have been studied less. It has previously been observed that elevated cardiac biomarkers may be observed after exercise, the significance of which is not known. LÄS MER

  4. 4. Cellular electrophysiological modulation in chronic atrial fibrillation - Studies with magnesium and GIK solution

    Författare :Max Ingemansson; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Action potential duration; Atrial cycle length; Atrial remodelling; Autonomic nervous system; AV-nodal; Conduction velocity; GIK; Magnesium; Resting membrane potential.; Refractoriness; Atrial fibrillation; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : Although chronic atrial fibrillation (CAF) is the most common sustained cardiac arrhythmia in man, the mechanisms involved in its progressive course are still not fully understood. Recent studies have verified an electrical remodelling of the atrial myocardium that may be responsible for the electrophysiological disturbances known to exist in the fibrillating atria. LÄS MER

  5. 5. Teratogenicity as a consequence of drug-induced embryonic cardiac arrhythmia : Common mechanism for almokalant, sotalol, cisapride, and phenytoin via inhibition of IKr

    Författare :Anna-Carin Sköld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; IKr; delayed rectifying K channel; embryonic cardiac arrhythmia; teratogenicity; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

    Sammanfattning : During the last years, drugs that prolong the repolarisation phase of the myocardial action potential, due to inhibition of the rapid component of the delayed-rectifying potassium channel (IKr) have been in focus. In addition to arrhythmogenic potential, selective Ikr-blockers have also been shown to be embryotoxic and teratogenic in animal studies. LÄS MER