Sökning: "dopamine"

Visar resultat 1 - 5 av 464 avhandlingar innehållade ordet dopamine.

  1. 1. Cooling and dopamine

    Författare :Roger Roscher; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; electrophysiology; cooling; Hypothermia; swine; lung transplantation; organ preservation; dopamine; circulation; contractility; oxygenation; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : There is little knowledge about the circulatory effects of dopamine in hypothermia. Induced hypothermia has been shown to improve outcome in various settings. Hypothermia is also used for preservation of organs that are harvested for transplantation. LÄS MER

  2. 2. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects

    Författare :Sara af Bjerkén; Ingrid Strömberg; Kathy Steece-Collier; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; GDNF; L-DOPA; L-DOPA induced dyskinesia; Neurobiology; Neurobiologi;

    Sammanfattning : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. LÄS MER

  3. 3. Nuclear medicine methods in idiopathic Parkinsonism : pre- and postsynaptic dopamine SPECT

    Författare :Susanna Jakobson Mo; Katrine Åhlström Riklund; Anne Larsson Strömvall; Lars Forsgren; Rimma Axelsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear medicine; SPECT; 123I-FP-Cit; 123I-IBZM; dopamine; parkinsonism; Parkinson’s disease; multiple system atrophy; progressive supranuclear palsy; Radiology; radiologi;

    Sammanfattning : Background: Single photon emission computed tomography (SPECT) with dopamine transporter (DAT) and dopamine D2 receptor (D2R) ligands can visualise the integrity of the nigrostriatal dopamine system. Parkinson’s disease (PD) and the atypical parkinsonian diseases (APD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA), have similar symptoms and dopamine depletion, but differ in pharmacological response and prognosis. LÄS MER

  4. 4. Aerobic fitness and healthy brain aging : cognition, brain structure, and dopamine

    Författare :Lars Jonasson; Carl-Johan Boraxbekk; Katrine Riklund; Emrah Düzel; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aerobic exercise; VO2; working memory; executive function; freesurfer; striatum; dopamine; D2-receptors; [11C]raclopride;

    Sammanfattning : Background: Performing aerobic exercise and maintaining high levels of aerobic fitness may have positive effects on both brain structure and function in older adults. Despite decades of research however, there is still a rather poor understanding of the neurocognitive mechanisms explaining the positive effects of aerobic exercise on cognition. LÄS MER

  5. 5. Dopamine D2 and D3 receptors. Studies on transduction mechanisms and on the role of a D3 gene polymorphism

    Författare :Monika Hellstrand; Göteborgs universitet; []
    Nyckelord :dopamine; dopamine D2 receptor; dopamine D3 receptor; transduction; CHO cells; partial agonism; inverse agonism; arachidonic acid; prostaglandin E2; cAMP; haloperidol; -3-PPP; PNU-99194A; polymorphism; personality;

    Sammanfattning : The neurotransmitter dopamine has been implicated in the pathophysiology of, e.g., Parkinson s disease and schizophrenia, and dopamine receptor-active compounds are commonly employed therapeutically in these and other disorders. LÄS MER