Sökning: "intestinal epithelial cells"

Visar resultat 26 - 30 av 149 avhandlingar innehållade orden intestinal epithelial cells.

1. 26. Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4

   Författare :Ramin Massoumi; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; PKC; vinculin; actin filament; focal adhesion; LTD4; integrin; cancerology; Cytologi; onkologi; cancer; Biochemistry; Metabolism; Biokemi; metabolism;

   Sammanfattning : Leukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. LÄS MER

3. 27. Signaling and regulation of cysteinyl leukotriene receptors in intestinal epithelial cells and colon cancer

   Författare :Astrid Bengtsson; Malmö Cellpatologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF alpha; COX-2; interferon alpha; all-trans retinoic acid; EGF; inflammation; colorectal cancer; CysLT2R; Leukotriene; CysLT1R;

   Sammanfattning : Colorectal cancer is the third most common type of cancer, and the second leading cause of cancer-related deaths in the Western world. Chronic inflammation, such as inflammatory bowel diseases (IBD), increases the risk of cancer. Cysteinyl leukotrienes are pro-inflammatory mediators that are involved in IBD. LÄS MER

4. 28. Paracellular permeability of intestinal epithelia.An in vivo study

   Författare :Britt-Marie Fihn; Göteborgs universitet; []
   Nyckelord :paracellular permeability; intestinal epithelia; deoxycholic acid; cholera toxin; glucose absorption; water transport;

   Sammanfattning : Aim: Investigate the importance of paracellular transport of water and solutes during physiological and pathophysiological conditions. Methods: The transport of small water-soluble inert permeability markers, was studied in jejunum and colon in anesthetized rats and cats during normal conditions and during exposure to cholera toxin (CT) and deoxycholic acid (DCA). LÄS MER

5. 29. Innate lymphoid cells and cholesterol metabolism in intestinal barrier function

   Författare :Sara Martina Parigi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The intestinal mucosa represents one of the largest barrier sites of our body, having to withstand a constant exposure to a plethora of environmental insults (including dietary compounds, xenobiotics, metabolites and microorganisms). While our body has evolved tolerance/ignorance towards some of these factors deemed beneficial for the host, it requires constant maintenance of epithelial barrier integrity and ability to mount pro-inflammatory responses to protect against potentially harmful environmental insults. LÄS MER

7. 30. Innate immunity of human intestinal epithelium in childhood celiac disease : influences from celiac disease associated bacteria and dietary oats

   Författare :Grzegorz Pietz; Marie-Louise Hammarström; Thomas T MacDonald; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; dietary oats; gut microbiota; intestinal epithelium; IEL; IFN-γ; IRF1; IL-18; CXC3L1; inflammasome; permeability; Prevotella jejuni; Lachnoanaerobaculum umeaense; immunologi; Immunology;

   Sammanfattning : Background & Aims: Celiac disease (CD) is a chronic inflammatory small-bowel enteropathy caused by permanent intolerance to gliadin in wheat gluten, and related proteins in ray and barley. It is disputed whether CD patients tolerate oats. The only treatment of CD is lifelong gluten-free diet (GFD). LÄS MER