Avancerad sökning
Visar resultat 1 - 5 av 149 avhandlingar som matchar ovanstående sökkriterier.
1. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers
Sammanfattning : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. LÄS MER
2. The interplay between Giardia intestinalis and host intestinal epithelial cells : A tale of immune activation and suppression
Sammanfattning : Giardia intestinalis is a non-invasive, protozoan parasite causing the diarrheal disease giardiasis in a variety of mammals, including humans. The parasite has two main life cycle stages; disease-causing trophozoites and infectious cysts. Trophozoites colonize the host’s upper small intestine by attaching to intestinal epithelial cells (IECs). G. LÄS MER
3. Butyrophilin- and Butyrophilin-like genes and their role in epithelial cell-intraepithelial T lymphocyte cross-talk
Sammanfattning : More than 50% of our immune system is located in the gut. The intestinal epithelium, which forms an interface between the organism and the environment, harbors intraepithelial lymphocytes (IELs) that comprise a mixture of conventional αβ T cells and unconventional αβ- and γδ T cells. LÄS MER
4. Defence capabilities of human intestinal epithelial cells
Sammanfattning : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. LÄS MER
5. Human intestinal epithelial cells in innate immunity : interactions with normal microbiota and pathogenic bacteria
Sammanfattning : Rod-shaped bacteria were previously shown to be associated with the small intestinal epithelium of children with celiac disease (CD). Using culture-dependent and independent methods, we characterized the microbiota of small intestine in children with CD and controls. The normal microbiota constitutes an unique organ-specific biofilm. LÄS MER