Sökning: "Malmö Cellpatologi"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Malmö Cellpatologi.

  1. 1. The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)

    Författare :Kishan Bellamkonda; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. LÄS MER

  2. 2. Signaling and regulation of cysteinyl leukotriene receptors in intestinal epithelial cells and colon cancer

    Författare :Astrid Bengtsson; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF alpha; COX-2; interferon alpha; all-trans retinoic acid; EGF; inflammation; colorectal cancer; CysLT2R; Leukotriene; CysLT1R;

    Sammanfattning : Colorectal cancer is the third most common type of cancer, and the second leading cause of cancer-related deaths in the Western world. Chronic inflammation, such as inflammatory bowel diseases (IBD), increases the risk of cancer. Cysteinyl leukotrienes are pro-inflammatory mediators that are involved in IBD. LÄS MER

  3. 3. Involvement of eicosanoid signalling in epithelial cell migration

    Författare :Oliver Broom; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histokemi; cytokemi; Medicin människa och djur ; Histology; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; Integrin; Eicosanoid; COX-2; Cell migration; cytochemistry; histochemistry; Histologi; tissue culture; vävnadskultur;

    Sammanfattning : The development of inflammatory bowel diseases (IBD) and colon cancer (CC) has been shown to involve the up-regulation of inflammatory mediators and the machinery producing them such as the eicosanoids. Changes in the expression of extracellular matrix proteins and their related integrin receptors have also been shown to be important in the advancement IBD and CC. LÄS MER

  4. 4. Anti-Tumor Effects of CysLT2R in Epithelial Cancer

    Författare :Cecilia Magnusson; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; migration; Colon cancer; breast cancer; EGF; interferon;

    Sammanfattning : The pro-inflammatory cysteinyl leukotrienes (cysLTs) are implicated in several pathological disorders, such as asthma and inflammatory diseases. The well-established connection between chronic inflammation and cancer implicates inflammatory mediators in cancer progression. It is therefore of interest to examine the effects of the CysLTs in cancer. LÄS MER

  5. 5. Role of novel tumor suppressors in colon cancer : Mechanisms and therapeutic opportunities

    Författare :LUBNA MEHDAWI; Malmö Cellpatologi; []
    Nyckelord :Tumor Suppressor Genes; 15-PGDH; WNT5A;

    Sammanfattning : Colon cancer is the third most common cancer in the world and the fourth most common cause of cancer related deaths. Inflammation is one of the risk factors for development of colon cancer. Interestingly immune cells as mast cells and inflammatory mediators as LTC4 play an important role in colon cancer. LÄS MER