Sökning: "intestinal epithelial cells"

Visar resultat 31 - 35 av 149 avhandlingar innehållade orden intestinal epithelial cells.

  1. 31. Translational studies of epithelial cancer

    Författare :Johanna Classon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumors stemming from specialized epithelial cells cause the most common cancer types and are among the leading causes of death in the western world. Although great strides have been made in early cancer detection, defining prognostic factors, and improving survival with novel treatments, cancers such as colorectal cancer and prostate cancer are incurable in their advanced stages. LÄS MER

  2. 32. Conséquences d’un stress chronique sur la barrière de mucus intestinal chez le rat : effet du probiotique Lactobacillus farciminis

    Författare :Stéphanie da Silva; Muriel Mercier-Bonin; Annick Bernadier-Donadille; Bruno Pot; Nathalie Juge; France Clermont Ferrand University UMR454 INRA; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background. Despite a large body of literature incriminating mucus alterations in the pathogenesis of Intestinal Bowel Diseases (IBD), structural and physical changes in the mucus layer remain poorly understood in the micro-inflammatory context of Irritable Bowel Syndrome (IBS). LÄS MER

  3. 33. Pivotal role of the nuclear receptor PPARgamma in colon epithelial cells

    Författare :Emmelie Å Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : When symbiosis between the residential intestinal flora and the epithelial cells of the gastrointestinal tract is broken one endpoint may be chronic inflammation, e.g. Inflammatory Bowel Disease (IBD). The disruption of the epithelial lining elicits activation of NF-kappaB and secretion of potent inflammatory mediators. LÄS MER

  4. 34. Signalling and activation of TLR4 by Gram-negative bacteria in epithelial cells

    Författare :Lisa Meijer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lipopolysaccharide (LPS) is a well-characterized pathogen-associated molecule found primarily as a constituent of the outer membrane of Gram-negative bacteria. LPS is known to act on different cell types in a pleiotropic manner. LÄS MER

  5. 35. The influence of nutritional status and age on chromatin structure and transcriptional activity in liver and intestinal epithelial cells

    Författare :Marie Norell; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytologi; Cellbiologi; Näringsfysiologi; Ämnesomsättning;

    Sammanfattning : All processes in mammals depend on regulated gene expression whichin turn depends on the amount and composition of the nutrient intake.Not only is the regulation of gene expression affected by nutrition butalso the structure of DNA and chromatin can be influenced. LÄS MER