Sökning: "deoxycholic acid"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden deoxycholic acid.
1. Paracellular permeability of intestinal epithelia.An in vivo study
Sammanfattning : Aim: Investigate the importance of paracellular transport of water and solutes during physiological and pathophysiological conditions. Methods: The transport of small water-soluble inert permeability markers, was studied in jejunum and colon in anesthetized rats and cats during normal conditions and during exposure to cholera toxin (CT) and deoxycholic acid (DCA). LÄS MER
2. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients
Sammanfattning : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. LÄS MER
3. Crohn's disease in Stockholm County : epidemiological panorama and associated gallstone disease
Sammanfattning : Crohn's disease is a chronic inflammatory bowel disease of obscure etiology, affecting any part of the gastrointestinal tract but the ileocaecal region in particular. The annual incidence has gradually been increasing, and the clinical pattern has changed; a shift towards colorectal involvement as well as an increasing number of elderly patients has been observed. LÄS MER
4. The interplay between bile acids and gut microbiota in metabolic and hepatobiliary disease
Sammanfattning : The gut microbiota, a metabolic regulator, orchestrates the production of bioactive metabolites such as secondary bile acids. Growing evidence suggests that shifts in the gut microbiota composition are linked to metabolic and hepatobiliary disease. LÄS MER
5. Collagenous colitis : The influence of inflammation and bile acids on intestinal barrier function
Sammanfattning : Background and aims: Collagenous colitis (CC) is a diarrheal disorder with an incidence rate of 5-6/100000 inhabitants, affecting mainly middle-aged women. The diagnosis is made by histology of the colonic mucosa. Classical findings are a thickened subepithelial collagenous layer and chronic inflammation in the lamina propria. LÄS MER