Sökning: "EGF"

Visar resultat 1 - 5 av 127 avhandlingar innehållade ordet EGF.

  1. 1. Tumour Targeting Using Radiolabelled EGF Conjugates Preclinical Studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Åsa Liljegren Sundberg; Jörgen Carlsson; Lars Gedda; Vladimir Tolmachev; Erik Blomquist; Gregory P. Adams; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; targeting; tumour; EGF; radionuclide; gefitinib; Iressa; ZD1839; glioma; therapy; diagnostics; Strålningsvetenskap; MEDICINE Physiology and pharmacology Radiological research Radiation biology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Strålningsbiologi;

    Sammanfattning : Tumour targeted radiotherapy is an appealing approach for treatment of disseminated tumour cells. A targeting agent that specifically binds to a structure on tumour cells is then used to transport therapeutically relevant radionuclides. The epidermal growth factor receptor, EGFR, is overexpressed on tumour cells in several malignancies, e.g. LÄS MER

  2. 2. Targeting to EGF receptors : effects of native or radiolabelled EGF on cultured glioma cells and its distribution in vivo

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jacek Capala; [1991]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  3. 3. Targeting to EGF receptors : preparation of EGF-dextran conjugates and analysis of their metabolism in vitro and in vivo

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Annelie Lindström; [1993]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 4. Targeting to EGF receptors : Preparation and experimental analysis of end-end coupled mEGF-dextran conjugates

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Qinghai Zhao; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Targeted tumor therapy is to deliver cytotoxic agents selectively to tumor cells. By such delivery, normal tissues receive minimal damage while a therapeutical effect is achieved in tumor. A targetingsystem can be constructed by conjugating a tumor-seeking molecule and toxic agents via a carrier. LÄS MER

  5. 5. Growth factor regulation of the urokinase plasminogen activator (uPA) system in human endometrium, and the significance of uPA receptor activation in endometrial angiogenesis

    Detta är en avhandling från Institutionen för Obstetrik och gynekologi, Universitetssjukhuset, 22185 Lund

    Författare :Tove Sandberg; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; endothelial cell migration; angiogenesis; uPA:PAI-1 complex; uPAR; TGF-beta; PAI-1; EGF; uPA; Growth factor; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : The purpose of this thesis was to examine the role of growth factors and the urokinase plasminogen activator (uPA) system in human endometrial angiogenesis. Growth factors as well as progesterone increased expression of the main inhibitor of uPA (PAI-1) in primary cultures of endometrial stromal cells. LÄS MER