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Visar resultat 1 - 5 av 113 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Does cancer originate in utero?

   Författare :Magnus Kaijser; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Epidemiology; prenatal exposure delayed effects; breast neoplasms; testicular neoplasms; lung neoplasms; pregnancy; estrogens; estriol; low birth weight body weight; height; twins; matemal exposure; smoking; infant premature; small for gestational age.;

   Sammanfattning : The purpose of the present thesis was to evaluate Trichopoulos' hypothesis that breast cancer can originate in utero, and to examine the role of antenatal estrogen exposure in the etiology of testicular cancer. First, we used data from a Swedish-Norwegian cohort study on risk factors for small-for-gestational-age births to identify markers for antenatal estrogen exposure. LÄS MER

3. 2. Targeted gene transfer in the developing central nervous system using viral vectors

   Författare :Simon Stott; Brain Repair and Imaging in Neural Systems (BRAINS); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; Medicin människa och djur ; Medicine human and vertebrates ; gene transfer; in utero; neonatal; GDNF; nigrostriatal; dopamine; AAV; retrovirus; neuropsykologi; neurofysiologi;

   Sammanfattning : Dopamine (DA) is a neurotransmitter that plays a fundamental role in many aspects of normal brain function. The majority of DA neurons in the brain reside in one region ? the midbrain ? and project axonal connections to specific areas. One of the main target regions of the DA system is the striatum. LÄS MER

4. 3. Gender inequity in child survival : travails of the girl child in rural north India

   Författare :Anand Krishnan; Nawi Ng; Peter Byass; Chadrakant Pandav; Per Ashorn; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Conditional cash transfers; girl child; inequities; gender; prejudice; mortality; non-specific effects; sex; socio-economic; vaccines; Epidemiology; epidemiologi;

   Sammanfattning : Background: While substantial progress has been made globally towards achieving United Nations Millennium Development Goal 4 (MDG 4) on child mortality, the decline is not sufficient to reach the targets set for 2015. The South Asian region, which includes India, was to achieve the MDG 4 target of 39 deaths per 1000 live births by 2015 but was estimated to have reached only 61 by 2011. LÄS MER

5. 4. Local Immune regulation in human pregnancy : with focus on decidual macrophages

   Författare :Charlotte Gustafsson Lidström; Christina Ekerfelt; Eva Sverremark-Ekström; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; placenta; leukocyte; ELISPOT; Clinical immunology; Klinisk immunologi;

   Sammanfattning : During pregnancy, the woman carries a fetus partly foreign to her immune system, because of the expression of paternal antigens. Despite this, the fetus is normally tolerated and not rejected, as is often the case with organs in allogeneic transplantations. LÄS MER

7. 5. Fetal Movements in late Pregnancy : Categorization, Self-assessment, and Prenatal Attachment in relation to women’s experiences

   Författare :Mari-Cristin Malm; Helena Lindgren; Ingela Rådestad; Christine Rubertsson; Siw Alehagen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fetal movements; pregnancy; prenatal attachment; self-assessment; stillbirth; Obstetrik och gynekologi; Obstetrics and Gynaecology; Hälsa och välfärd;

   Sammanfattning : Aim: To explore how pregnant women experience fetal movements in late pregnancy. Specific aims were:  to study women’s experiences during the time prior to receiving news that their unborn baby had died in utero (I), to investigate women’s descriptions of fetal movements (II), investigate the association between the magnitude of fetal movements and level of prenatal attachment (III), and to study women’s experiences using two different self-assessment methods (IV). LÄS MER