Sökning: "matemal exposure"

Hittade 4 avhandlingar innehållade orden matemal exposure.

  1. 1. Metabolism of inorganic arsenic and biomarkers of exposure

    Författare :Gabriela Concha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Arsenic; metabolism; methylation; biomarker; infant; children; women; drinking water; breast milk;

    Sammanfattning : Humans as well as most mammals metabolize inorganic arsenic (Inorg As), a recognized human carcinogen, by methylation. The end-metabolites methylarsonic acid (MMA) and dimethylarsinic acid (DMA) are less toxic and more readily excreted in the urine than Inorg As. LÄS MER

  3. 2. Does cancer originate in utero?

    Författare :Magnus Kaijser; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epidemiology; prenatal exposure delayed effects; breast neoplasms; testicular neoplasms; lung neoplasms; pregnancy; estrogens; estriol; low birth weight body weight; height; twins; matemal exposure; smoking; infant premature; small for gestational age.;

    Sammanfattning : The purpose of the present thesis was to evaluate Trichopoulos' hypothesis that breast cancer can originate in utero, and to examine the role of antenatal estrogen exposure in the etiology of testicular cancer. First, we used data from a Swedish-Norwegian cohort study on risk factors for small-for-gestational-age births to identify markers for antenatal estrogen exposure. LÄS MER

  4. 3. Organohalogen contaminants in humans with emphasis on polybrominated diphenyl ethers

    Författare :Daiva Meironyté Guvenius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The occurrence and distribution of organohalogen compounds, including polybrominated diphenyl ethers (PBDEs), in humans was investigated. For this purpose, the previously used method for analysis of organochlorine compounds was modified for the analysis of PBDEs and hydroxylated metabolites of polychlorinated biphenyls (OH-PCBs) in breast milk, matemal and cord blood plasma, liver and adipose tissue. LÄS MER

  5. 4. Atopic dermatitis : clinical and epidemiological aspects in children up to four years

    Författare :Maria Böhme; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atopy; childhood; criteria; eczema; heredity; IgE; infections; prevention; sensitisation; severity;

    Sammanfattning : Atopic dermatitis (AD) is a pruritic, chronically relapsing inflammatory skin disease; its aetiology is presumed to be multifactorial with interactions between genetic and environmental factors. In recent decades the prevalence of AD has increased remarkably, most likely due to environmental factors in early life. LÄS MER