Sökning: "focal cerebral ischemia"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden focal cerebral ischemia.

  1. 11. Brain Tissue Oxygenation in Traumatic Brain Injury : Experimental and Clinical Studies

    Författare :Karlis Purins; Anders Lewén; Per Enblad; Oliver Sakowitz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain tissue oxygenation; Cerebral metabolism; Traumatic brain injury; Cerebral ischemia; Threshold levels; Neurovent-PTO; Microdialysis; Neurosurgery; Neurokirurgi;

    Sammanfattning : Traumatic brain injury (TBI) is a major cause of death and disability. TBI is frequently followed by cerebral ischemia which is a great contributor to secondary brain damage. The main causes of cerebral ischemia are pathophysiological changes in cerebral blood flow and metabolism. LÄS MER

  2. 12. Importance of MAPK and PKC in cerebrovascular endothelin receptor changes

    Författare :Marie Henriksson; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; farmakognosi; farmaci; toxikologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; Kardiovaskulära systemet; Cardiovascular system; Fysiologi; Physiology; cerebral arteries; ischemia; receptors; endothelin; Farmakologi;

    Sammanfattning : Endothelin is a vasoactive peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating vasodilatation. LÄS MER

  3. 13. Neurointensive care of subarachnoid hemorrhage : Clinical and neurochemical aspects

    Författare :Kristina Giuliana Cesarini; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; SAH; neurointensive care; neurochemical monitoring; cerebral ischemia; microdialysis; cerebral metabolism; secondary ischemic events; clinical outcome; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

    Sammanfattning : Neurointensive care (NIC) has gained terrain in the treatment of patients with various acute cerebral conditions. It is based on the concept that an unfavorable clinical outcome, to a certain extent, results from all secondary ischemic insults sustained by the brain during the acute phase of the disease. LÄS MER

  4. 14. Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach

    Författare :Tomas Olsson; Neuroinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; Neurologi; neuropsychology; Neurology; global; hypothermia; hsp70; receptor; adenosine A1; NMDA; cystatin C; cell death; hippocampus; Brain; ischemia; neurophysiology;

    Sammanfattning : Brain ischemia is a major cause of death and morbidity in the industrialized countries. It is mainly caused by stroke, but may also be the consequence of successful cardiopulmonary resuscitation in victims of cardiac arrest, known as transient global ischemia. LÄS MER

  5. 15. The role of the complement system in arthritis and stroke

    Författare :Max Albert Hietala; Göteborgs universitet; []
    Nyckelord :complement; C3; factor B; transgenic knockout; arthritis; focal cerebral ischemia;

    Sammanfattning : Complement is part of the innate immune system and functions primarily as a first line of defense against invading microorganisms. It is a complex cascade, which can be activated via three pathways: the classical, alternative and mannan-binding lectin pathway. LÄS MER