Sökning: "cerebral arteries"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden cerebral arteries.

  1. 1. Blood flow assessment in cerebral arteries with 4D flow magnetic resonance imaging : an automatic atlas-based approach

    Författare :Tora Dunås; Anders Eklund; Anders Wåhlin; Jan Malm; Einar Heiberg; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Circle of Willis; 4D flow MRI; Cerebral arteries; Vascular disease; Stroke; Automatic labeling; Probabilistic atlas; Cerebral blood flow; Neuroimaging; Magnetic Resonance Imaging;

    Sammanfattning : Background: Disturbed blood flow to the brain has been associated with several neurological diseases, from stroke and vascular diseases to Alzheimer’s and cognitive decline. To determine the cerebral arterial blood flow distribution, measurements are needed in both distal and proximal arteries. LÄS MER

  2. 2. Signal Transduction and Gene Regulation in Cerebral Arteries Following Ischemia

    Författare :Petter Vikman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Cardiovascular system; stroke; molecular investigation; gene expression; Mitogen Activated Protein Kinases; Natural science; Kardiovaskulära systemet; cerebral arteries;

    Sammanfattning : The thesis consideres the molecular events that take place in the cerebral arteries following a stroke. The degree and temporal course of reperfusion following a stroke is pivotal for the survival of the neuronal tissue in the penumbra. LÄS MER

  3. 3. Cerebral blood flow distribution, collateral function and pulsatility in healthy and in patients with symptomatic carotid stenosis  : a magnetic resonance imaging approach

    Författare :Laleh Zarrinkoob; Jan Malm; Anders Eklund; Khalid Ambarki; Sepideh Amin-Hanjani; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aging; Arterial pulsatility; Carotid stenosis; Cerebral arteries; Cerebral blood flow; Cerebral collateral blood flow; Circle of Willis; Phase contrast magnetic resonance imaging;

    Sammanfattning : Background: For the detection and treatment of early cerebral vascular disease it is of paramount importance to first understand the normal physiology of the cerebral vasculature, and subsequently, to understand how and when pathology can develop from that. This is especially important as the population above 65 years of age is increasing and aging itself is an established risk factor for the development of cerebral vascular disease. LÄS MER

  4. 4. Receptor Upregulation and MAPK Activity in Arteries and Bronchi Following Secondhand Smoke Exposure

    Författare :Lei Cao; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary arteries; cerebral arteries; 5-hydroxytryptamine receptor; endothelin receptor; secondhand smoke exposure; bronchi;

    Sammanfattning : Cigarette smoking is a major risk factor for cardiovascular and respiratory diseases. Contractile receptor changes have been observed in several vascular diseases. The intracellular mitogen activated protein kinase (MAPK) signaling pathways are suggested to be associated with receptor upregulation. LÄS MER

  5. 5. A study of potassium channel activation as a pharmacological principle for vasodilation of cerebral blood vessels

    Författare :Torsten Ryman; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; cerebral arteries; Cerebral ischemia; Potassium channel openers; vascular endothelium; EDHF; KRN2391; KATP; Pinacidil; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Increasing [K+]o is intimately coupled to progressive ischemia and reduced CBF. In isolated cerebral and mesenteric arteries, it was found that significant differences in the vascular responses to [K+]o exist. Among the species studied, human cerebral arteries were the most sensitive artery to increasing [K+]o. LÄS MER