Sökning: "The complement system"

Visar resultat 16 - 20 av 532 avhandlingar innehållade orden The complement system.

  1. 16. The role of the complement system in basal and ischemia-induced neurogenesis

    Författare :Yalda Rahpeymai Bogestål; Göteborgs universitet; []
    Nyckelord :complement; C3a; C5a; adult neurogenesis; neural stem cells; brain ischemia;

    Sammanfattning : .... LÄS MER

  3. 17. Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

    Författare :Göran Jönsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; mykologi; bakteriologi; virologi; Mikrobiologi; mycology; Complement; Complement C2 deficiency; Infectious diseases; Atherosclerosis; SLE; Autoantibodies; GM allotypes; Immunodeficiency state; Medicine human and vertebrates ; Medicin människa och djur ; Microbiology; virology; bacteriology; Immunologi; serologi; Infections; Infektioner;

    Sammanfattning : The complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. LÄS MER

  4. 18. Interactions between Streptococcus pyogenes and the Human Immune System

    Författare :Maria Weineisen; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; virologi; mykologi; Immunology; mycology; Mikrobiologi; bakteriologi; virology; Biomedicinska vetenskaper; Neutrophils; Streptococcus pyogenes; Biomedical sciences; Phagocytosis; bacteriology; Microbiology; Integrins;

    Sammanfattning : Streptococcus pyogenes is a common human pathogen causing mild infections such as tonsillitis and pharyngitis, but is also the cause of life-threatening conditions. To be able to infect the human host, S. pyogenes express different virulence factors. The surface-expressed M protein is a major virulence factor of S. LÄS MER

  5. 19. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

    Författare :Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER

  7. 20. The Role of Fc Gamma Receptors in Experimental Arthritis

    Författare :Maria Andrén; Sandra Kleinau; Birgitta Heyman; Roland Jonsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Rheumatoid arthritis; Antibodies; Fc receptors; Complement; Transgenic Knockout mice; Immunologi; Immunology; Immunologi;

    Sammanfattning : Induction of collagen-induced arthritis (CIA), an animal model for human rheumatoid arthritis, is dependent on anti-collagen type II (CII) antibodies. The effector mechanism by which autoantibodies contribute to inflammatory reactions in autoimmune diseases is not well understood. LÄS MER