Sökning: "Complement"

Visar resultat 1 - 5 av 1101 avhandlingar innehållade ordet Complement.

  1. 1. Rules of engagement - Regulation of complement response in tissue

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Anas Haider Abu-Humaidan; Lunds universitet.; Lund University.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; Complement activation; Complement regulation; terminal complement complex; Staphylococcus auereus; atopic dermatitis; head and neck cancer; epidermal growth factor receptor; EGFR;

    Sammanfattning : Always in motion and probing for danger, complement proteins are found in every space and notch of the body. Their omnipresence combined with an ability to wreak havoc when activated, mandates a strong leash! The how, when, and where to unleash or constrain the complement response remain partly answered questions, despite the significant progress made in the field in the past 100 years. LÄS MER

  2. 2. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Detta är en avhandling från Divison of Medical Microbiology

    Författare :Gunilla Nordin Fredrikson; Lunds universitet.; Lund University.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Popular Abstract in Swedish Ärftlig brist på vissa proteiner ökar risken för autoimmun sjukdom eller svår hjärnhinneinflammation I blodbanan finns ett 30-tal olika proteiner som ingår i den del av vårt immunförsvar som kallas komplementsystemet. Detta systems huvudsakliga uppgifter är att förinta oönskade inkräktare, såsom bakterier och virus, samt eliminera skadliga proteinkomplex som cirkulerar i blodbanan. LÄS MER

  3. 3. Complement in Disease - Extracellular Proteins as Complement Regulators

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Kaisa Happonen; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; joint disease; Complement; proteoglycan; cancer;

    Sammanfattning : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. LÄS MER

  4. 4. The Role of IgM and Complement in Antibody Responses

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christian Rutemark; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Complement; antibody response; mutated IgM; natural IgM; complement receptors; SIGN-R1; SAP; CRP; B cells; Medical Science; Medicinsk vetenskap;

    Sammanfattning : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. LÄS MER

  5. 5. Complement Activation Triggered by Biomaterial Surfaces Mechanisms and Regulation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jonas Andersson; Uppsala universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Biomaterials; Biocompatibility; Blood; Complement; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; klinisk immunologi; Clinical Immunology;

    Sammanfattning : Today there are a vast number of medical devices in temporary or permanent contact with human tissues. Blood-biomaterial contact is known to trigger the complement system and results in generation of fluid phase anaphylatoxins C3a and C5a, and surface-bound C3b and iC3b. LÄS MER