Sökning: "C5a"
Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet C5a.
1. C5a Receptor Expression in Severe Sepsis and Septic Shock
Sammanfattning : In patients with sepsis, the activation of the cascade systems, for example the complement system with the generation of C5a, is followed by a state of immunosuppression with impaired bactericidal capacity caused by suppression of the neutrophil granulocytes. To inhibit the C5a-induced systemic inflammatory and the following anti-inflammatory responses, different anti-C5a strategies have been successful in experimental models of sepsis. LÄS MER
2. The role of the complement system in basal and ischemia-induced neurogenesis
Sammanfattning : .... LÄS MER
3. Molecular analysis of Streptococcus pyogenes and its interactions with the human host
Sammanfattning : Streptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. LÄS MER
4. Regulation of human eosinophil transmigration across lung epithelium
Sammanfattning : Eosinophil infiltration into the lung tissues and airways is a hallmark of allergic asthma. To reach the lung lumen, eosinophils migrate across the vascular endothelium, through the interstitial matrix and across lung epithelium. LÄS MER
5. Analysis of the molecular interplay between Streptococcus pyogenes and its human host
Sammanfattning : The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. LÄS MER