Sökning: "innate immune response"

Visar resultat 1 - 5 av 358 avhandlingar innehållade orden innate immune response.

  1. 1. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response

    Författare :Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER

  3. 2. Haemophilus influenzae adhesins and the innate immune response

    Författare :Elena Ronander; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Haemophilus influenzae; Haemophilus surface fibrils; complement; innate immune response; protein E; respiratory epithelium; adhesins;

    Sammanfattning : Haemophilus influenzae is a human specific Gram-negative respiratory tract pathogen. Encapsulated H. influenzae strains exist in six different serotypes a-f, of which type b (Hib) is the most virulent. Hib is protected by the polysaccharide capsule when invading the blood circulaton and may cause diseases such as meningitis and epiglottitis. LÄS MER

  4. 3. Innate immune cell response in sepsis

    Författare :Yongzhi Wang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; abdominal sepsis; neutrophil; monocyte; platelet; coagulation; lung;

    Sammanfattning : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. LÄS MER

  5. 4. Regulatory aspects of innate immune responses

    Författare :Ahmed El Marghani; Per-Erik Olsson; Peter Kjellén; Muhammad Zafarullah; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Innate immunity; TOM1L1; inflammatory responses; Biology; Biologi;

    Sammanfattning : Activation of innate immunity is regulated by a variety of signaling molecules within the immune cells. The present thesis was aimed to improve our understanding of innate signaling mechanism and their possible use as bio-indicators of exposure and disease. LÄS MER

  7. 5. Innate immune response in human endothelial cells : characterization and regulation of E-selectin, ICAM-I and cytokine expression and the role of Staphylococcus aureus

    Författare :Jan Strindhall; Åsa Ljungh; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Endothelial cells located on the vessel walls play an important role in inflammation. In response to cytokines or other inflammatory mediators such as microorganisms, endothelial cells express cell adhesion molecules such as E-selectin and ICAM-1 that are involved in binding circulating leukocytes to the endothelium. LÄS MER