Sökning: "Antibodies"
Visar resultat 1 - 5 av 1732 avhandlingar innehållade ordet Antibodies.
1. Diabetes mellitus in Adults - Aspects of Incidence, Autoimmunity and C-peptide
Sammanfattning : Type 1 and type 2 diabetes increase worldwide, leading to a heavy burden of disease and its complications. All 1666 adults aged 18-100 years with new onset diabetes in Kronoberg during 3 years were registered, and type of diabetes classified by pancreatic autoantibodies and C-peptide. LÄS MER
2. Platforms and strategies harnessing signaling pathways of multifactorial diseases by multispecific antibodies
Sammanfattning : Abstract [ENG]Proteins govern a multitude of biological functions vital to sustain life. The ability to withstand diseases development and harboring a defense against foreign pathogens is attributed to the wonders of the immune system and the proteins and cells its comprised of. LÄS MER
3. SOD1 misfolding and aggregation in ALS : in the light of conformation-specific antibodies
Sammanfattning : Mutations in the superoxide dismutase 1 (SOD1) gene are linked to the progressive neurodegenerative disease amyotrophic lateral sclerosis (ALS). ALS-associated mutations affect the stability of the SOD1 protein and promote its unfolding. As a consequence, disordered SOD1 species can misfold and accumulate into insoluble aggregates. LÄS MER
4. Canine heterophilic antibodies
Sammanfattning : Anamnesis, physical examination and laboratory testing are the pillars of the clinical diagnostic procedure. Alas, laboratory tests are not perfect and analytical errors happen, which can lead to misdiagnosis and detrimental consequences for patient care. LÄS MER
5. Antibodies during pregnancy : Aspects on complications during pregnancy and complications related to transfusion
Sammanfattning : The fetus acquires half of its genetic infonnation from the father and represents a foreign graft in pregnancy. The overall mechanisms contributing to immunologic tolerance and successful pregancy still are an enigma. Accumulating results of immunologic research, however, offer an explanation for many events in pregnancy. LÄS MER