Sökning: "dendritic cells"

Visar resultat 1 - 5 av 365 avhandlingar innehållade orden dendritic cells.

  1. 1. Human dendritic cells : a study of early events during pathogen recognition and antigen endocytosis

    Författare :Peter Hellman; Malmö högskola; []

    Sammanfattning : The mononuclear phagocyte cell system includes monocytes, macrophages anddendritic cells which are important cells in order to recognize, ingest, destroyand also present part of a pathogen to T-lymphocytes in order to activate theadaptive immune system. Dendritic cells (DCs) stand out in their ability tostimulate T-lymphocytes and are also believed to be important to keeptolerance for “self-antigens”. LÄS MER

  2. 2. Dendritic cells in cancer immunotherapy

    Författare :Karin Gustafsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :vaccines; dendritic cells; αDC1; PGE2DC; natural killer cells; T cells;

    Sammanfattning : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. LÄS MER

  3. 3. Approaches to analyses of cytotoxic cells. And studies of their role in H. pylori infection

    Författare :Josef Azem; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Helicobacter pylori; mucosal immunology; stomach; duodenum; asymptomatic; duodenal ulcer; gastric adenocarcinoma; NK cells; T cells; B cells; dendritic cells; cytotoxic;

    Sammanfattning : Helicobacter pylori infection causes chronic gastritis that may progress to peptic ulcers or gastric adenocarcinoma and thereby cause major world-wide health problems. Previous studies have shown that CD4+ T cells and the production of the cytokine IFN- × are important components of the immune response to H. pylori in humans. LÄS MER

  4. 4. The ontogeny and function of intestinal dendritic cells

    Författare :Emma Persson; Slemhinnans immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenteric lymph nodes; Intestine; Dendritic cells; Gut-homing; Th17 cells; Oral tolerance; Immunity;

    Sammanfattning : The intestinal mucosa presents a huge surface area to the external environment and the intestinal immune system is continually exposed to a wide array of foreign antigens derived from resident intestinal microbiota as well as dietary constituents, including food proteins. In order to maintain intestinal homeostasis, the intestinal immune system relies on the ability to generate tolerogenic responses to innocuous antigen while maintaining the ability to develop effective immune responses to intesinal pathogens. LÄS MER

  5. 5. Endocytosis by human dendritic cells

    Författare :Linda Andersson; Malmö högskola; []
    Nyckelord :human dendritic cells; endocytosis;

    Sammanfattning : Dendritic cells (DCs) are specialized antigen-presenting cells with the ability to internalize antigen, and present antigen-derived peptides to T cells. The functions of DCs depend on the subset, as well as their location and activation state. LÄS MER