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Visar resultat 1 - 5 av 532 avhandlingar som matchar ovanstående sökkriterier.
1. Accuracy, efficiency and robustness for rigid particle simulations in Stokes flow
Sammanfattning : The thesis concerns simulation techniques for systems of nano- to micro-scaled rigid particles immersed in a viscous fluid, ubiquitous in nature and industry. With negligible fluid inertia, the set of PDEs known as the Stokes equations can be used to model the hydrodynamics. LÄS MER
2. Crosstalk Between Activated Platelets and the Complement System
Sammanfattning : Several studies have shown that complement and thrombotic events co-exist. Platelets have been suspected to act as the bridge between the two cascade systems. LÄS MER
3. The Role of IgM and Complement in Antibody Responses
Sammanfattning : An intact complement system including the complement receptors 1 and 2 (CR1/2) is crucial for the generation of a normal antibody response in animals and humans. Moreover, activation of the classical pathway is thought to be important since deficiency in complement components C1q, C2, C4 or C3 lead to impaired antibody responses. LÄS MER
4. The complement system in stherosclerosis and arthritis
Sammanfattning : The complement system plays an essential role in the humoral immune response. Activated complement has diverse functions, including the initiation of inflammation, recruitment of leukocytes, clearance of immune complexes, neutralization of pathogens, regulation of antibody responses and disruption of cell membranes. LÄS MER
5. Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defence
Sammanfattning : The C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. LÄS MER