Sökning: "TLR signaling"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden TLR signaling.
1. Intracellular regulation of TLR signaling Basic mechanisms and importance in intestinal inflammation
Sammanfattning : Toll-like receptors (TLRs) recognize conserved structures on/in microorganisms. The intracellular signalling pathways of TLRs are shared with IL-1R and IL-18R and their activation leads to transcription of proinflammatory cytokines and type-I interferons. LÄS MER
- Detta är en avhandling från Institutionen för Experimentell Medicinsk Vetenskap, Lunds Universitet
Sammanfattning : Macrophages play an essential role in the defense against infection by phagocytosis and by production of inflammatory mediators. Such mediators are TNF? and eicosanoids. Many microbial agents elicit arachidonate release in macrophages that lead to the formation of eicosanoids. LÄS MER
- Detta är en avhandling från Örebro : Örebro university
Sammanfattning : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. LÄS MER
4. Development of novel immunization approaches to generate immunity in the female genital tract with special reference to genital herpesDetta är en avhandling från Göteborg : Göteborg University
Sammanfattning : Development of mucosal vaccines for inducing immunity in the female reproductive tract would have profound implications for the prevention of sexually transmitted diseases. Despite numerous efforts, no such vaccines are currently available for human use. LÄS MER
5. Effects of Complement Opsonization of HIV on Dendritic Cells and Implications for the Immune ResponseDetta är en avhandling från Linköping : Linköping University Electronic Press
Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER