Sökning: "Birgitta Heyman"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Birgitta Heyman.

1. 1. Regulation of the immune response by IgM and IgG antibodies

   Författare :Birgitta Heyman; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

3. 2. The Role of Fc Gamma Receptors in Experimental Arthritis

   Författare :Maria Andrén; Sandra Kleinau; Birgitta Heyman; Roland Jonsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Rheumatoid arthritis; Antibodies; Fc receptors; Complement; Transgenic Knockout mice; Immunologi; Immunology; Immunologi;

   Sammanfattning : Induction of collagen-induced arthritis (CIA), an animal model for human rheumatoid arthritis, is dependent on anti-collagen type II (CII) antibodies. The effector mechanism by which autoantibodies contribute to inflammatory reactions in autoimmune diseases is not well understood. LÄS MER

4. 3. A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses

   Författare :Joakim Bergström; Birgitta Heyman; Jenny Hallgren Martinsson; Frida Henningsson Johnson; Mats Bemark; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FcγR; complement; sheep erythrocytes; IgG-mediated immune suppression; rhesus prophylaxis; rhesus D antigen; germinal center; Immunologi; Immunology;

   Sammanfattning : Antibodies passively administered together with their specific antigen can enhance or suppress the specific antibody response. This phenomenon is known as antibody feedback regulation. Whether this modulation causes up- or downregulation of the antibody response depends both on the antibody isotype and the antigen used. LÄS MER

5. 4. Antibody Feedback Regulation and T Cells

   Författare :Fredrik Carlsson; Birgitta Heyman; Alf Grandien; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fc receptors; B cell; T cell; antigen presentation; complement receptors; complement; IgE; IgG3; CD23; antibody; Immunology; Immunologi;

   Sammanfattning : Antibodies, passively administered or actively produced, regulate immune responses to the antigen they recognize. This phenomenon is called antibody-mediated feedback regulation. Feedback regulation can be positive or negative, resulting in >1000-fold enhancement or >99% suppression of the specific antibody response. LÄS MER

7. 5. The Significance of IgG Antibodies against Tissue Transglutaminase in Coeliac Disease

   Författare :Ingrid Dahlbom; Birgitta Heyman; Tony Hansson; Knut Lundin; Uppsala universitet; []
   Nyckelord :Immunology; Coeliac disease; Tissue transglutaminase; Endomysium; IgG antibodies; Immunologi;

   Sammanfattning : Coeliac disease (CD) is a multifactorial disease of the small intestine. In genetically predisposed individuals the, ingestion of cereals leads to a remodulation of the mucosal architecture, and the production of autoantibodies against tissue transglutaminase (tTG). The treatment is a lifelong gluten-free diet. LÄS MER