Sökning: "DNA quantification"
Visar resultat 6 - 10 av 105 avhandlingar innehållade orden DNA quantification.
6. Evolving the Methodology for Detection of Primary DNA Damage : Development, adaptation and assessment of the single cell gel electrophoresis (comet) assay
Sammanfattning : Deoxyribonucleic acid (DNA) is one of the most important molecules in nature. It is the fundamental carrier of evolutionary information and constitutes the genetic blueprint of all living organisms. Being the sole source of information, it is vital for the cell to transmit the correct genetic information from generation to generation. LÄS MER
7. Quantification of Radiation Induced DNA Damage Response in Normal Skin Exposed in Clinical Settings
Sammanfattning : The structure, function and accessibility of epidermal skin provide aunique opportunity to study the DNA damage response (DDR) of a normaltissue. The in vivo response can be examined in detail, at a molecularlevel, and further associated to the structural changes, observed at atissue level. LÄS MER
8. Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates
Sammanfattning : This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their reaction products (adducts) with biomacromolecules. LÄS MER
9. Genital human papillomaviruses. Studies of their occurrence, type spectrum and expression
Sammanfattning : The occurrence of genital human papillomavirus infection was determined in different categories of patients by means of PCR. In high proportion of young women attending an adolescent clinic, the presence of HPV DNA was demonstrated in simultaneously urethral and cervical samples, suggesting that genital HPV infections are often multifocal. LÄS MER
10. Organic phosphorus speciation in environmental samples : Method development and applications
Sammanfattning : This thesis investigates the development of new methodology for the identification and quantification of organic phosphorus compounds in environmental samples.Phosphorus is a vital element for primary production and one of the factors contributing to eutrophication. LÄS MER
