Sökning: "Kimmo Peltonen"

Hittade 2 avhandlingar innehållade orden Kimmo Peltonen.

1. 1. Biomarkers aiming at cancer risk estimation of polycyclic aromatic hydrocarbons

   Författare :Hans Helleberg; Kimmo Peltonen; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

   Sammanfattning : Polycyclic aromatic hydrocarbons (PAH), a family of compounds that are formed in incomplete combustion of organic matter, occur as general pollutants in air and food. Exposure to PAH is, according to preliminary estimates, associated with non-acceptable cancer risks showing the need for improved data to be used in risk estimation. LÄS MER

3. 2. Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates

   Författare :Emelie Westberg; Margareta Törnqvist; Kimmo Peltonen; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biomarker; PAH; serum albumin; adduct; DNA; isocyanate; miljökemi; Environmental Chemistry;

   Sammanfattning : This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their reaction products (adducts) with biomacromolecules. LÄS MER