Sökning: "CA Andersson"

Visar resultat 6 - 10 av 32 avhandlingar innehållade orden CA Andersson.

1. 6. Functional role of a constitutively active dioxin/Ah receptor in a transgenic mouse model

   Författare :Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dioxin Ah receptor; TCDD; dioxin; stomach tumor; osteopontin; peritoneal B1 B cells; transcription factor; gene expression;

   Sammanfattning : The dioxin/ Aryl hydrocarbon receptor is a ligand-activated transcription factor that mediates most (if not all) of the toxic effects of the group of highly potent environmental pollutants collectively called dioxins and PCBs, including the highly toxic compound 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD). The toxic effects include immune suppression, endocrine disruption, impaired reproduction and carcinogenesis. LÄS MER

3. 7. Process analytical methods for monitoring of the film coating on pharmaceutical pellets and tablets using NIR spectrometry and image analysis

   Författare :Martin Andersson; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PLS; PCA; PAC; NIR; chemometrics; moving samples; information depth; release rate; image analysis; near infrared; process analytical chemistry; thickness; coating; film; tablets; Pellets; granules; Analytical chemistry; Analytisk kemi;

   Sammanfattning : Pharmaceutical tablets and pellets are often covered with a coating. There is a need for methods that enable monitoring of the growth of such films during processing. Such analyses can be performed using process analytical chemical methods based on near infrared (NIR) diffuse reflectance spectrometry. It provides with analyses that take only ca. LÄS MER

4. 8. Sveconorwegian orogenesis in the southwestern Baltic Shield - Zircon geochronology and tectonothermal setting of orthogneisses in SW Sweden

   Författare :Jenny Andersson; Berggrundsgeologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Petrology; Geologi; fysisk geografi; physical geography; Geology; structural markers; augen gneiss; orthogneiss; migmatite; ion microprobe; Pb-Pb evaporation; U-Pb; geochronology; zircon; Sweden; Mylonite Zone; Western Segment; Sveconorwegian orogen; Eastern Segment; mineralogy; geochemistry; Petrologi; mineralogi; geokemi;

   Sammanfattning : The Mylonite zone (MZ) is a prominent late-Sveconorwegian lithological terrane boundary in the SW Baltic Shield along which large-scale crustal block movements took place during the Sveconorwegian orogeny. The southern section of the MZ also defines a conspicuous metamorphic break separating upper amphibolite and high-pressure granulite facies rocks in the parautochthonous Eastern Segment (ES), from middle amphibolite facies rocks in the overlying Western Segment (WS). LÄS MER

5. 9. Gene Expression Studies of Hematologic Malignacies

   Författare :Anna Andersson; Avdelningen för klinisk genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; cancer; onkologi; Cytologi; oncology; Cytology; acute myeloid leukemia; acute lymphoblastic leukemia; normal hematopoietic cells; cDNA microarray; gene expression profiling; hematopoiesis; pediatric leukemia; fusion gene; Pediatrics; Pediatri; Clinical genetics; Klinisk genetik; cancerology; Hematologi; extracellulära vätskor;

   Sammanfattning : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. LÄS MER

7. 10. Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies

   Författare :Ellen Andersson; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; acute pancreatitis; active site inactivated factor VII; bleeding; coagulation; factor VII; FVIIai; hemorrhagic complications; hemorrhage; interleukin-6; MIP-2; nuclear factor kappa B; tissue factor;

   Sammanfattning : In various inflammatory conditions a close interplay between inflammation and coagulation is known to exist, where coagulation factor VII (FVII) and tissue factor (TF) are considered to be pivotal players. In this thesis the crosstalk between inflammation and coagulation in acute pancreatitis (AP) has been investigated. LÄS MER