Sökning: "Centrum för analys och syntes"

Visar resultat 1 - 5 av 252 avhandlingar innehållade orden Centrum för analys och syntes.

1. 1. Biologically active terpenoids from Bolivian medicinal plants

   Författare :Maribel Lozano Palacios; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bolivian plants; cytotoxicity; triterpenes; damsin; breast cancer;

   Sammanfattning : Pseudo-guaianolides represent a large group of sesquiterpene lactones exhibiting significant cytotoxic and anti-inflammatory activities. Their biological activities are due to a 훼-methylene-훾-lactone unit in their chemical structure, which reacts with free sulfhydryl groups of free cysteine via a Michael-addition. LÄS MER

3. 2. Metabolites of Avena sativa with Blood Cholesterol Lowering Properties

   Författare :Narda Thuresson; Centrum för analys och syntes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholesterol lowering effect; Avena sativa; phytosterols; avenanthramides; 13-HODE;

   Sammanfattning : Cardiovascular diseases are among the most important causes of death in thedeveloped countries. These diseases are partly caused by too high cholesterolconcentrations in the blood. Avena sativa, oat, is the most common spieces of the genus Avena, and produced in huge amounts worldwide. LÄS MER

4. 3. Microphase Separated Cation Conducting Polymers : Design, Synthesis, and Properties

   Författare :Hannes Nederstedt; Centrum för analys och syntes; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; ENGINEERING AND TECHNOLOGY; Polymer; Litiumbatteri; Mikrofasseparering; Bränslceller; Elektrolyt; Polymerelektrolyt; Polymera bränslecellsmembran; Polymer electrolyte fuel cells; Polymer electrolyte; Polymer electrolyte membrane; Microphase separation; Lithium battery; Polymer; Fuel cell; Proton exchange membrane PEM ;

   Sammanfattning : This thesis describes the synthesis and properties of five different cation conducting polymer systems. These systems were designed so that the polymers would be able to microphase separate into distinct phases with one phase for mechanical strength and one for ionic conductivity. LÄS MER

5. 4. Design, Synthesis and Thermodynamic Studies of Galectin Ligands

   Författare :Maria Luisa Verteramo; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; ENGINEERING AND TECHNOLOGY; galectin; conformational entropy; solvation; thermodynamic; interaction; molecular recognition; thiodigalactoside; diastereomer; structure-based design;

   Sammanfattning : The signaling within and between cells in biology is governed by molecular recognition between natural or synthetic ligands and proteins. This thesis project aimed to investigate the thermodynamic properties of specific interaction between synthetic ligands and galectin proteins. LÄS MER

7. 5. Design and Synthesis of Glycomimetics as Selective Galectin Inhibitors

   Författare :Mukul Mahanti; Centrum för analys och syntes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Galectin; Galectin inhibitors; Glycomimentics; Epimeric switch; MD simulation;

   Sammanfattning : In last couple of decades the field of glycobiology has developed rapidly due to the increased understanding of glycans’ abilities to encode biological information, which may have impact on biological event and disease, such as for example tumour growth and inflammation. This development has been accompanied by an increasing focus on drug discovery revolving around a category of carbohydrate-based drugs termed glycomimetics. LÄS MER