Sökning: "peritoneal B1 B cells"

Hittade 1 avhandling innehållade orden peritoneal B1 B cells.

1. 1. Functional role of a constitutively active dioxin/Ah receptor in a transgenic mouse model

   Författare :Patrik Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Dioxin Ah receptor; TCDD; dioxin; stomach tumor; osteopontin; peritoneal B1 B cells; transcription factor; gene expression;

   Sammanfattning : The dioxin/ Aryl hydrocarbon receptor is a ligand-activated transcription factor that mediates most (if not all) of the toxic effects of the group of highly potent environmental pollutants collectively called dioxins and PCBs, including the highly toxic compound 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD). The toxic effects include immune suppression, endocrine disruption, impaired reproduction and carcinogenesis. LÄS MER